75100-21-9Relevant academic research and scientific papers
Synthesis of 4-amino-4,5-dideoxy-L-lyxofuranose derivatives and their evaluation as fucosidase inhibitors
Chevrier, Carine,Le Nou?n, Didier,Defoin, Albert,Tarnus, Céline
, p. 1202 - 1211 (2011/07/09)
The nitrone 4 (4,5-dideoxy-4-hydroxylamino-3,4-O-isopropylidene-L- lyxofuranose) was synthesised from d-ribose and used as key intermediate for the preparation of fucosidase inhibitors. We describe two transformations of 4. Hydrolysis with aqueous sulfur
Nitrone in L-lyxose series: Cycloaddition way for the synthesis of new C-α-fucosides
Chevrier, Carine,LeNouen, Didier,Neuburger, Markus,Defoin, Albert,Tarnus, Céline
, p. 5363 - 5366 (2007/10/03)
Nitrone 3 analogue of 5-deoxy-L-lyxose was derived from D-ribose. Its reduction with aqueous SO2 gave the corresponding 4-amino-sugar 2, a potent α-L-fucosidase inhibitor. 1,3-Dipolar cycloaddition of 3 with alkenes allowed the synthesis of ace
The Photochemistry of Ketones derived from Carbohydrates. Part 9. Formation of O- and C-Ribofuranoside Derivatives by Photodecarbonylation of O-and C-Glycosides of lyxo-Hexopyranos-4-ulose Derivatives
Collins, Peter M.,Travis, Anthony S.
, p. 779 - 786 (2007/10/02)
The syntheses of 6-deoxy-2,3-O-isopropylidene-α-L-lyxo-hexopyranosyl-4-ulose-ethane (7) and -benzene (8), and the assignment of their anomeric configurations by 1H and 13C n.m.r. spectroscopy, are described.The preparations of a number of O-glycosid-4-ulo
