740816-14-2

Usage

Reaction

Reagent used in the highly enantioand diastereoselective, catalytic intramolecular Stetter reaction. Direct synthesis of α-protio and α-deuterio α-chloro and α-fluoro carboxylic acids via assymetric hydration. Chemoselective conversion of α-unbranched aldehydes to amides.

Upstream product

• 862095-79-2 indeno[2,1-b]-1,4-oxazin-3(2H)-one,4,4a,9,9a-tetrahydro-,(4aR,9aS)- 
• 420-37-1 trimethoxonium tetrafluoroborate 
• 122-51-0 orthoformic acid triethyl ester 
• 828-73-9 pentafluorophenyl hydrazine 
• 4441-15-0 morpholin-2-one 
• 108-90-7 chlorobenzene 

Relevant academic research and scientific papers

Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof

Provided herein are triazolium carbine catalysts useful for asymmetric hydration, fluorination, and deuteration, and processes for their preparation. Also provided are synthetic reactions in which these catalysts are used, in particular, in stereoselective formation of carbon-chlorine, carbon-hydrogen, carbon-fluorine, and carbon-deuterium bonds.

An efficient synthesis of achiral and chiral 1,2,4-triazolium salts: Bench stable precursors for N-heterocyclic carbenes

The promising utility of triazolyl N-heterocyclic carbene catalysts in umpolung aldehyde chemistry requires a straight-forward reliable synthesis from readily available materials. Herein, we describe the synthesis of a variety of triazolyl N-heterocyclic