740836-05-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 73814-98-9 (2R,3S)-5-Benzyloxy-2-methyl-pentane-1,3-diol 
• 909803-77-6 (2S,3S)-5-Benzyloxy-3-hydroxy-2-methyl-pentanal 
• 19790-60-4 3-Benzyloxypropanal 
• 909803-71-0 (3S,4R)-1-Benzyloxy-4-methyl-hex-5-en-3-ol 

Downstream Products

• 740836-18-4 (2R,3S,5S,6R)-5,7-Bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-1-phenylsulfanyl-heptan-3-ol 
• 740836-19-5 (2R,3S,5S,6R)-1-Benzenesulfonyl-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-heptan-3-ol 
• 740836-03-7 [(2R,3S,5S,6R)-5,7-Bis-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-2,6-dimethyl-heptane-1-sulfonyl]-benzene 
• 740836-27-5 (2R,3S,5S,6S,9R,10S)-9-(3,4-Dimethoxy-benzyloxymethoxy)-5-methoxy-10-((2R,3R)-5-methoxy-3-methyl-tetrahydro-furan-2-yl)-2,6-dimethyl-undecane-1,3-diol 
• 740836-06-0 (R)-4-Benzyl-3-[(2R,3S,5S,6R)-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,6-dimethyl-heptanoyl]-oxazolidin-2-one 
• 740836-11-7 (2R,3R)-2-[(E)-(1S,2R,5S,6S,8S,9R)-2-Benzyloxy-8,10-bis-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-1,5,9-trimethyl-dec-3-enyl]-5-methoxy-3-methyl-tetrahydro-furan 
• 740836-26-4 (2R,3R)-2-[(1S,2R,5S,6S,8S,9R)-8,10-Bis-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dimethoxy-benzyloxymethoxy)-6-methoxy-1,5,9-trimethyl-decyl]-5-methoxy-3-methyl-tetrahydro-furan 
• 740836-12-8 (2R,3R)-2-[(1S,2R,5S,6S,8S,9R)-8,10-Bis-(tert-butyl-diphenyl-silanyloxy)-2-(3,4-dimethoxy-benzyloxymethoxy)-6-methoxy-1,5,9-trimethyl-decyl]-5-methoxy-3-methyl-tetrahydro-furan 
• 740836-13-9 (3R,4R,5R,6R,9S,10S,12S,13R)-12,14-Bis-(tert-butyl-diphenyl-silanyloxy)-6-(3,4-dimethoxy-benzyloxymethoxy)-10-methoxy-3,5,9,13-tetramethyl-tetradecane-1,4-diol 
• 909803-74-3 (3R,4R,5R,6R,9S,10S,12S,13R)-12,14-Bis-(tert-butyl-diphenyl-silanyloxy)-6-(3,4-dimethoxy-benzyloxymethoxy)-10-methoxy-3,5,9,13-tetramethyl-1-trityloxy-tetradecan-4-ol 

Relevant academic research and scientific papers

Synthesis and biological activity of mycalolide analogs

Mycalolide analog 4, consisting only of the side chain of mycalolide B (2), a trisoxazole macrolide of marine origin, was stereoselectively synthesized using Roush crotylboration, an Evans aldol reaction, and a Paterson aldol reaction as key steps. The an

Synthesis and actin-depolymerizing activity of mycalolide analogs

Mycalolide analog 4, consisting only of the side chain of mycalolide B (2), was stereoselectively synthesized and was found to have strong actin-depolymerizing activity.