741-75-3Relevant academic research and scientific papers
Molybdenum-mediated synthesis of quinazolin-4(3H)-ones via cyclocarbonylation using microwave irradiation
Roberts, Bryan,Liptrot, David,Luker, Tim,Stocks, Michael J.,Barber, Catherine,Webb, Nicola,Dods, Robert,Martin, Barrie
supporting information; experimental part, p. 3793 - 3796 (2011/08/06)
A new, efficient and practical synthesis of quinazolin-4(3H)-ones is reported via molybdenum-mediated cyclocarbonylation using microwave irradiation. These methods allow access to a wide range of quinazolin-4(3H)-ones in reasonable yields without the need for gaseous carbon monoxide and palladium catalysts. A range of reactions illustrating the wide scope of this chemistry was carried out and all proceeded in reasonable yields.
A facile synthesis of 2-amino-3H-quinazolin-4-ones with tandem aza- Wittig reaction
Ding, Ming-Wu,Zeng, Gui-Ping,Wu, Tian-Jie
, p. 1599 - 1604 (2007/10/03)
2-Amino-3H-quinazolin-4-ones 8 were prepared from tandem aza-Wittig reaction of iminophosphorane 5 with aromatic isocyanate and nucleaphilic reagent HY in mild condition.
