32045-49-1

Upstream product

• 64-17-5 ethanol 
• 118-92-3 anthranilic acid 

Downstream Products

• 55301-25-2 Benzyloxycarbonyl-alanylanthranilsaeureethylester 
• 72758-41-9 2-{[(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carbonyl]-amino}-benzoic acid ethyl ester 
• 72758-45-3 2-{[(2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carbonyl]-amino}-benzoic acid ethyl ester 
• 23961-11-7 N-phenylalanyl-anthranilic acid 
• 55301-37-6 Benzyloxycarbonylglycyl-alanylanthranilsaeureethylester 
• 1025937-27-2 2-(3-chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester 
• 622403-42-3 1-phenyl-3-(2-ethoxycarbonylphenyl) carbodiimide 
• 622403-43-4 2-(4-Chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester 
• 741-75-3 2-(piperidin-1-yl)-3-phenylquinazolin-4(3H)-one 
• 741-76-4 2-(morpholin-4-yl)-3-phenylquinazolin-4(3H)-one 

Relevant academic research and scientific papers

Organosilicon synthesis of isocyanates: III. Synthesis of aliphatic, carbocyclic, aromatic, and alkylaromatic isocyanatocatboxylic acid esters

A series of aminoacid esters was prepared by treating the aminoacid suspensions in ethanol with thionyl chloride. Best conversion of aminoacid esters to corresponding isocyanates was achieved in the case of aromatic and carbocyclic aminoesters by phosgeneation of their N-silyl derivatives, and in the case of aliphatic and alkylaromatic aminoesters by phosgeneation of O-silyl or N,O-bissilylurethanes on their basis. In the last case additional step of esterification of the by-products isocyanatoalkylcarboxylic acid chlorides is required after phosgeneation. Unusual generation of cynnamates and intramolecular N→O-migration of trimethylsilyl group in the solutions of silylated alkylaromatic β-aminoacid esters were found. Pleiades Publishing, Inc., 2006.

A facile synthesis of 2-amino-3H-quinazolin-4-ones with tandem aza- Wittig reaction

2-Amino-3H-quinazolin-4-ones 8 were prepared from tandem aza-Wittig reaction of iminophosphorane 5 with aromatic isocyanate and nucleaphilic reagent HY in mild condition.

Synthesis and spectroscopic characterisation of 13C-labelled anthranilic acid

The three isotopomers (1-13C)-, (2-13C)-, and (6-13C)- anthranilic acid (2-aminobenzoic acid) have been synthesised from simple 99% 13C-labelled starting materials. The isotopomers have been characterised using mass spectrometry, 1H-NMR spectroscopy and 13C-NMR spectroscopy. The spectroscopic results confirm that, within experimental error, the syntheses were accomplished without scrambling or dilution of label. The labelled anthranilic acids are used as substrates for bioconversion into the correspondingly labelled L-tryptophans. For this purpose, the (2-13C)- label has been synthesised on the gram scale.