74117-31-0

Basic information

• Product Name: 1H-Indole-1-carboxylic acid, phenyl ester
• Synonyms: 1H-Indole-1-carboxylic acid,phenyl ester;N-Phenoxycarbonylindole;phenyl 1H-indole-1-carboxylate;1-phenoxycarbonyl indole
• CAS NO: 74117-31-0
• Molecular Formula: C15H11NO2
• Molecular Weight: 237.258
• Mol File: 74117-31-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1H-Indole-1-carboxylic acid, phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-1-carboxylic acid, phenyl ester(74117-31-0)
• EPA Substance Registry System: 1H-Indole-1-carboxylic acid, phenyl ester(74117-31-0)

Safety Data

• Hazardous Substances Data: 74117-31-0(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 1885-14-9 phenyl chloroformate 
• 139-02-6 sodium phenoxide 
• 109241-96-5 indole-1-carboxylic acid anhydride 
• 102-09-0 bis(phenyl) carbonate 
• 13884-13-4 indole-1-carboxylic acid 
• 530-62-1 1,1'-carbonyldiimidazole 
• 108-95-2 phenol 

Downstream Products

• 140887-32-7 (3aS,3bS,8aS,8bR)-2,3,3a,3b,8a,8b-Hexahydro-1H-8-aza-cyclopenta[3,4]cyclobuta[1,2-a]indene-8-carboxylic acid phenyl ester 
• 140887-32-7 (3aR,3bS,8aS,8bS)-2,3,3a,3b,8a,8b-Hexahydro-1H-8-aza-cyclopenta[3,4]cyclobuta[1,2-a]indene-8-carboxylic acid phenyl ester 

Relevant articles and documents

An easy-to-operate n-carbonylation of indoles with diaryl carbonates as reagent and Na2CO3 as catalyst

Na2CO3 catalyzed N-carbonylation of indoles using diaryl carbonates as acylation reagent have been developed. It provided an efficient and simple method for the utilization of carbonates and the synthesis of N-carbonyl indoles. The reaction can be operated easily with Na2CO3 as catalyst in CH3CN and the corresponding products were isolated with good to excellent yields.

A simple direct phosgeneless route to N-heteroaryl unsymmetrical ureas

A new simple approach to the synthesis of unsymmetrical ureas HetNC(O)NRR′ (HetNH = pyrrole, indole, carbazole; R, R′ = H, alkyl, aryl) has been explored, which involves the direct reaction of the N-phenoxycarbonyl derivatives of pyrrole, indole and carba

Superbase-promoted direct N-carbonylation of pyrrole with carbonic acid diesters

Carbonic acid diesters have been investigated as carbonylating agents in the direct reaction with pyrrole (HetNH). In the presence of superbases (DBU, P1-t-Bu, BTPP) as catalysts, the heteroaromatic substrate can be N-carbonylated by direct reaction with carbonic acid diesters under not-severe experimental conditions. The carbonylation reaction makes accessible pyrrole N-carbonyl derivatives (HetNC(O)OR, (HetN)2CO) selectively through a simple straightforward way, which offers a safe eco-friendly alternative to the traditional synthetic methods based on hazardous phosgene or phosgene-derivatives.