741265-59-8Relevant academic research and scientific papers
Asymmetric Total Synthesis of TAN-1085 Facilitated by Pd-Catalyzed Atroposelective C-H Olefination
Fan, Jun,Yao, Qi-Jun,Liu, Yan-Hua,Liao, Gang,Zhang, Shuo,Shi, Bing-Feng
, (2019)
Asymmetric total synthesis of TAN-1085 via Pd-catalyzed atroposelective C-H olefination is described. This synthesis features the gram-scale construction of axially chiral biaryls in an enantiopure form employing the readily available l-tert-leucine as th
Concise total synthesis and structure assignment of TAN-1085
Ohmori, Ken,Mon, Keiji,Ishikawa, Yuji,Tsuruta, Hideyuki,Kuwahara, Shunsuke,Harada, Nobuyuki,Suzuki, Keisuke
, p. 3167 - 3171 (2007/10/03)
Rapid access to the tetracyclic core of TAN-1085 (1) was possible by exploiting three efficient processes: a tandem electrocyclic reaction (A), a pinacol cyclization (B), and a regioselective monobenzoylation of a 1,2-diol (C), which allowed the first total synthesis of 1.
