74135-10-7

Basic information

• Product Name: Sucrose octasulfate sodium salt
• Synonyms: SUCROSE OCTASULFATE SODIUM SALT;SODIUM SUCROSE OCTASULFATE;1,3,4,6-Tetra-O-sulfo-β-D-fructofuranosyl α-D-Glucopyranoside 2,3,4,6-Tetrakis(hydrogen sulfate) SodiuM Salt;10kg;a-D-Glucopyranoside,1,3,4,6-tetra-O-sulfo-b-D-fructofuranosyl, 2,3,4,6-tetrakis(hydrogen sulfate), sodiuM salt (1:8);sodium salt of sucrose octasulfate;sucrose octasulphate sodium salt;sucrose-octa-O-sulphonic acid sodium salt
• CAS NO: 74135-10-7
• Molecular Formula: C₁₂H₁₄O₃₅S₈*8Na
• Molecular Weight: 1158.66
• EINECS: 1592732-453-0
• Product Categories: Oligosaccharide Compounds;Oligosaccharides;Sulfur & Selenium Compounds
• Mol File: 74135-10-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 159-164°C
• Appearance: White Powder
• Density: 2.097 at 20℃
• Storage Temp.: -20°C Freezer
• Solubility: Water (Sparingly, Sonicated)
• Stability: Hygroscopic
• CAS DataBase Reference: Sucrose octasulfate sodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: Sucrose octasulfate sodium salt(74135-10-7)
• EPA Substance Registry System: Sucrose octasulfate sodium salt(74135-10-7)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 74135-10-7(Hazardous Substances Data)

Usage

Chemical Properties

Sucrose octasulfate sodium salt is White Powder

Uses

Different sources of media describe the Uses of 74135-10-7 differently. You can refer to the following data:
1. Used as a reference standard for the drug Sucralfate
2. Sodium sucrose octasulfate is a chemical compound, and it has been used clinically for the prevention of gastrointestinal ulcers and was found to have cytoprotective effects. The sodium compounds are contents of various cosmetics for skin care and it was also evaluated in patients with cancer for the prevention and management of radiodermatitis.
3. Used as a reference standard for the drug Sucralfate.

InChI:InChI=1/C12H22O35S8.8Na/c13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18;;;;;;;;/h4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36);;;;;;;;/q;8*+1/p-8/t4-,5-,6-,7-,8+,9-,10+,11-,12+;;;;;;;;/m1......../s1

Upstream product

• 74135-13-0 ammonium salt of sucrose octasulfate 
• 74135-09-4 barium salt of sucrose octasulfate 
• 57-50-1 Sucrose 

Relevant articles and documents

HYPERSULFATED GLUCOPYRANOSIDES

Hypersulfated disaccharides, preferably octasulfated sucrose, with utility in asthma or asthma related disorders are disclosed. The compounds may optionally be formulated with pharmaceutically acceptable excipients or delivery agents. The delivery agents are selected from the group consisting of natural or synthetic polymers, aerosols or other vehicles that facilitate the delivery or administration of the drug. The hypersulfated disaccharides are made from carbohydrate starting materials. Ion exchange or other suitable synthetic processes may be utilized to prepare the pharmaceuticals. The hypersulfated disaccharides are useful as anti-inflammatory agents.

Method for preparing high potency sucralfate

Sucralfate is prepared in good yields and in newly useful form first by reacting sucrose with chlorosulfonic acid in 2-picoline. The amonium salt is then formed and reacted with aluminum chlorohydrate in specific sequence and alcoholic solvent. The two distinct products have unexpected pharmaceutical and physical characteristics. The oral liquid suspensions also must be critically formulated.