74149-52-3

Upstream product

• 15601-07-7 2-(3,5-dimethoxyphenyl)acetyl chloride 
• 671795-46-3 sec-butylmagnesium bromide 
• 74149-58-9 2-(3,5-dimethoxyphenylmethyl)-2-s-butyl-1,3-dithian 
• 69178-00-3 2-sec-butyl[1,3]dithiane 
• 877-88-3 3,5-dimethoxybenzyl bromide 
• 4670-10-4 (3,5-dimethoxyphenyl)acetic acid 

Downstream Products

• 35051-93-5 2-(3,5-Dimethoxy-phenyl)-4-methylhexanon-3 
• 33004-60-3 2-(3,5-dihydroxyphenyl)-4-methylhexan-3-one 
• 76151-05-8 2-sec-Butyl-2-[1-(3,5-dimethoxy-phenyl)-ethyl]-[1,3]dithiolane 
• 74149-53-4 2-(2-formyl-3,5-dihydroxyphenyl)-4-methylhexan-3-one 
• 74149-57-8 2-(2-methoxycarbonyl-3,5-dihydroxyphenyl)-4-methylhexan-3-one 
• 74149-55-6 [2-(1,3-Dimethyl-2-oxo-pentyl)-4,6-dihydroxy-phenyl]-oxo-acetonitrile 

Relevant academic research and scientific papers

Acetogenin Synthesis. Organocopper Reagents, Anions of 1,3-Dithians and of Protected Cyanohydrins as Intermediates in Ketide Side-chain Synthesis

The synthesis is reported of 3-s-butyl-4-methyl-3,6,8-trihydroxy-3,4-dihydroisocoumarin (1a) and 3-(1-methylprop-1-enyl)-4-methyl-3,6,8-trihydroxy-3,4-dihydroisocoumarin (1b) using organocopper reagents and anions of 1,3-dithians for compound (1a), and an

Biosynthesis of Ascochitine and Synthesis of its Biogenetic Precursors

'Enzymic trap' experiments show that the main biosynthetic pathway to ascochitine (1) involves the direct reduction of the enzyme-bound ester into aldehyde (4).Therefore the complete pathway has now been assessed.Various synthetic approaches have been tri