74152-14-0

Upstream product

• 74360-15-9 1,6-diphenyl-4-methyl-2-(1H)pyrimidinethione 
• 87797-59-9 6-methyl-3,4-diphenyl-1,3-diazabicyclo<2.2.0>hex-5-en-2-one 
• 64-10-8 phenyl carbamate 
• 93-91-4 1-phenylbutan-1,3-dione 
• 103-85-5 monophenylthiourea 
• 34954-21-7 3,4-dihydro-6-methyl-3,4-diphenylpyrimidin-2(1H)-one 
• 76387-96-7 4-methyl-2-methylthio-1,6-diphenyl-1,2-dihydropyrimidinium 

Downstream Products

• 1008-74-8 5-methyl-3-phenylisoxazole 
• 87797-59-9 6-methyl-3,4-diphenyl-1,3-diazabicyclo<2.2.0>hex-5-en-2-one 
• 74359-98-1 3,4-dihydro-4-methyl-1,6-diphenylpyrimidin-2(1H)-one 
• 34954-21-7 3,4-dihydro-6-methyl-3,4-diphenylpyrimidin-2(1H)-one 
• 90128-39-5 3-(N',N'-diethylureido)-1-phenyl-3-phenyliminobut-2-ene 

Relevant academic research and scientific papers

Novel Synthesis of 2,4-Diarylquinolines by Photochemical followed by Thermal Transformations of 1,4,6-Triarylpyrimidin-2(1H)-ones

The 2,4-diarylquinolines (3) were obtained in a one-pot synthesis by photochemical and subsequent thermal reactions of 1,4,6-triarylpyrimidin-2(1H)-ones (1) in fair yield.The quinolines (3) were formed via thermal cycloreversion, followed by electrocyclic ring-closure, of the 1,3-diazabicyclohex-5-en-2-ones (2), which were produced by photochemical electrocyclization of the pyrimidin-2(1H)-ones (1).

The Selective Preparation of 1,4-Diaryl-6-methyl- and 1,6-Diaryl-4-methyl-2-(1H)pyrimidinones

N-Phenylurea reacted with benzoylacetone derivatives (I) to give 1,4-diaryl-6-methyl-2-(1H)pyrimidinones (II) in addition to low yields of 1,6-diaryl-4-methyl-2-(1H)pyrimidinones (IV), while N-phenylthiourea afforded only 1,6-diaryl-4-methyl-2-(1H)pyrimidinethiones (III) in good yields.Further 1,6-diaryl-4-methyl-2-(1H)pyrimidinethiones (III) were succesfully converted in satisfactory yields into the corresponding 2-(1H)pyrimidinones (IV) by the treatment with methyl iodide in the presence of sodium methoxide in methanol at room temperature.

FACILE OXIDATION OF 2-OXO-1,4,6-TRISUBSTITUTED 1,2,3,6-TETRAHYDROPYRIMIDINES WITH CHLORANIL

2-Oxo-1,4,6-trisubstituted 1,2,3,6-tetrahydropyrimidines (1a-1h) were easily oxidized with 2,3,5,6-tetrachloro-1,4-benzoquinone (chloranil) to afford the corresponding 1,4,6-trisubstituted 2(1H)-pyrimidones (2) in good yields.