74201-84-6Relevant academic research and scientific papers
Imidazolidone derivative and synthesis method thereof
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Paragraph 0010; 0011; 0014, (2017/10/13)
The invention discloses an imidazolidone derivative and a synthesis method thereof. The name of the derivative is (5S)-3-cyclohexyl-2,4-dicarbonyl-1,3-diazabicyclo[3,3,0]octane. The synthesis method comprises the following steps: 1, synthesizing N-t-butyloxycarboryl-L-proline; 2, synthesizing N-t-butyloxycarboryl-L-prolyl-dicyclohexylurea; 3, synthesizing (5S)-3-cyclohexyl-2,4-dicarbonyl-1,3-diazabicyclo[3,3,0]octane. According to the synthesis method, the number of reaction steps is relatively small, the yield is relatively high, and the defects of a lot of reaction steps, complicated post-treatment, low yield and the like of the conventional synthesis of an imidazolidone compound are overcome; the novel imidazolidone derivative is prepared, which can meet the demand for industrial production of the imidazolidone compound.
