74205-15-5

Basic information

• Product Name: 1-(3-METHOXYPHENYL)CYCLOBUTANECARBONITRILE
• Synonyms: 1-(3-METHOXYPHENYL)CYCLOBUTANECARBONITRILE;1-Cyano-1-(3-methoxyphenyl)cyclobutane
• CAS NO: 74205-15-5
• Molecular Formula: C₁₂H₁₃NO
• Molecular Weight: 187.24
• Product Categories: Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 74205-15-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(3-METHOXYPHENYL)CYCLOBUTANECARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-METHOXYPHENYL)CYCLOBUTANECARBONITRILE(74205-15-5)
• EPA Substance Registry System: 1-(3-METHOXYPHENYL)CYCLOBUTANECARBONITRILE(74205-15-5)

Safety Data

• Hazardous Substances Data: 74205-15-5(Hazardous Substances Data)

Usage

General Description

1-(3-Methoxyphenyl)cyclobutanecarbonitrile is a chemical compound with the molecular formula C12H13NO, which consists of a cyclobutane ring with a phenyl group and a cyano group attached to it. It is a crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. This chemical is known for its potential biological and pharmacological activities, and it is often studied for its interactions with various biological targets. Its unique structure and properties make it a valuable building block for the development of new drugs and other important compounds.

Upstream product

• 19924-43-7 3-methoxyphenylacetonitrile 
• 109-64-8 1,3-dibromo-propane 

Downstream Products

• 803640-24-6 sec-Butyl-[1-(3-methoxy-phenyl)-cyclobutylmethyl]-amine 
• 709604-36-4 Diethyl-[1-(3-methoxy-phenyl)-cyclobutylmethyl]-amine 
• 732206-01-8 Ethyl-[1-(3-methoxy-phenyl)-cyclobutylmethyl]-amine 
• 61492-38-4 (2S,5R,6R)-6-{[1-(3-Methoxy-phenyl)-cyclobutanecarbonyl]-amino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 74205-43-9 1-(3-methoxy-phenyl)-cyclobutanecarboxylic acid 
• 92902-95-9 C-[1-(3-Methoxy-phenyl)-cyclobutyl]-methylamine 

Relevant articles and documents

Synthesis method of arylcyclobutane compound

The present invention discloses a method for synthesizing an arylcyclobutane compound to 1eq phenylacetonitrile and 1.1eq 1-bromo-3-chloropropane as raw material, N,N- dimethylacetamide as a solvent, plus 2.5eq sodium hydride, under the protection of iner

Oxadiazole Amine Derivative Compounds as Histone Deacetylase 6 Inhibitor, and the Pharmaceutical Composition Comprising the same

The present invention relates to a novel compound having an activity of inhibiting histone deacetylase 6 (HDAC6), an optical isomer thereof or a pharmaceutically acceptable salt thereof, a use thereof for preparation of a drug for treatment, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing the same. The novel compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof according to the present invention has an activity of inhibiting histone deacetylase 6 (HDAC6), and is effective for preventing or treating HDAC6-related diseases, including infectious diseases; neoplasm; endocrine, nutritional and metabolic diseases; mental and behavior disorders; nerve disorders; eye and adnexa diseases; cardiovascular diseases; respiratory diseases; digestive organ diseases; skin and subcutaneous tissue diseases; musculoskeletal and connective tissue diseases; or congenital malformation, deformation and chromosomal abnormality.COPYRIGHT KIPO 2017

5-lipoxygenase inhibitors

Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having the following formula I: STR1 and the pharmaceutically acceptable salts thereof, wherein Ar1 is a heterocyclic moiety which is selected from imidazolyl, pyrrolyl, py