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1-(3-methoxyphenyl)cyclobutanecarboxylic acid is a cyclobutanecarboxylic acid derivative characterized by a white solid appearance and a molecular formula of C13H14O3, with a molecular weight of 218.25 g/mol. It is distinguished by the presence of a methoxy group on the phenyl ring and a cyclobutane ring, which endows it with unique chemical properties and reactivity. 1-(3-methoxyphenyl)cyclobutanecarboxylic acid is a significant component in the realm of organic synthesis and medicinal chemistry, primarily utilized as a precursor for the synthesis of pharmaceuticals and biologically active molecules.

74205-43-9

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74205-43-9 Usage

Uses

Used in Organic Synthesis:
1-(3-methoxyphenyl)cyclobutanecarboxylic acid is used as a building block in organic synthesis for its ability to contribute to the formation of complex organic compounds through various chemical reactions. Its unique structural features facilitate the creation of a wide range of organic molecules with potential applications in different fields.
Used in Medicinal Chemistry:
In the pharmaceutical industry, 1-(3-methoxyphenyl)cyclobutanecarboxylic acid is used as a key intermediate in the development of new drugs. Its specific chemical properties allow for the design and synthesis of biologically active molecules that can target various therapeutic areas, potentially leading to the discovery of novel treatments for a range of diseases.
Used in Drug Development:
1-(3-methoxyphenyl)cyclobutanecarboxylic acid is employed as a starting material in drug development, where its reactivity and structural attributes are leveraged to create new pharmaceutical entities. 1-(3-methoxyphenyl)cyclobutanecarboxylic acid's potential to be modified and functionalized makes it a valuable asset in the synthesis of innovative drug candidates with improved efficacy and selectivity.
Overall, 1-(3-methoxyphenyl)cyclobutanecarboxylic acid's versatility in chemical reactions and its applicability in medicinal chemistry make it an indispensable tool in the synthesis of new organic compounds and the advancement of pharmaceutical research.

Check Digit Verification of cas no

The CAS Registry Mumber 74205-43-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,2,0 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 74205-43:
(7*7)+(6*4)+(5*2)+(4*0)+(3*5)+(2*4)+(1*3)=109
109 % 10 = 9
So 74205-43-9 is a valid CAS Registry Number.

74205-43-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(3-methoxyphenyl)cyclobutane-1-carboxylic acid

1.2 Other means of identification

Product number -
Other names 1-Carboxy-1-(3-methoxyphenyl)cyclobutane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:74205-43-9 SDS

74205-43-9Relevant academic research and scientific papers

Synthesis method of arylcyclobutane compound

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Paragraph 0130-0133; 0158-0161, (2022/01/10)

The present invention discloses a method for synthesizing an arylcyclobutane compound to 1eq phenylacetonitrile and 1.1eq 1-bromo-3-chloropropane as raw material, N,N- dimethylacetamide as a solvent, plus 2.5eq sodium hydride, under the protection of iner

Iridium-Catalyzed Enantioselective C(sp3)–H Borylation of Cyclobutanes

Chen, Xiang,Chen, Lili,Zhao, Hongliang,Gao, Qian,Shen, Zhenlu,Xu, Senmiao

, p. 1533 - 1537 (2020/09/09)

We herein report the first example of iridium-catalyzed enantioselective C(sp3)–H borylation of cyclobutanes using benzoxazoline as the directing group. The combination of a chiral bidentate boryl ligand and an iridium precursor has found to effectively catalyze C(sp3)–H borylation to afford a variety of cyclobutylboronates with good to excellent enantioselectivities. We also demonstrate the synthetic utility of the current method by converting the stereogenic C—B bond to other functionalities.

Arylcycloalkane carboxylic esters, their use, pharmaceutical compositions and preparation

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, (2008/06/13)

PCT No. PCT/SE97/01310 Sec. 371 Date Apr. 12, 1999 Sec. 102(e) Date Apr. 12, 1999 PCT Filed Jul. 23, 1997 PCT Pub. No. WO98/04517 PCT Pub. Date Feb. 5, 1998This invention relates to the use of 2-(diisopropylamino)-ethyl-1-phenyl-cyclopentane-carboxylate or 2-(diisopropylamino)-ethyl-1-phenyl-cyclohexane-carboxylate, or a pharmaceutically accceptable salt thereof, for treatment of urinary incontinence or irritable bowel syndrome (IBS).

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