742109-02-0

Basic information

• Product Name: (4S,5S)-4-Benzyl-5-(2-ethoxycarbonyl-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester
• Synonyms: (4S,5S)-4-Benzyl-5-(2-ethoxycarbonyl-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester
• CAS NO: 742109-02-0
• Molecular Weight: 391.508
• Mol File: 742109-02-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,5S)-4-Benzyl-5-(2-ethoxycarbonyl-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-4-Benzyl-5-(2-ethoxycarbonyl-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(742109-02-0)
• EPA Substance Registry System: (4S,5S)-4-Benzyl-5-(2-ethoxycarbonyl-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(742109-02-0)

Safety Data

• Hazardous Substances Data: 742109-02-0(Hazardous Substances Data)

Upstream product

• 742109-00-8 ethyl (2R,3S)-3-acetylamino-2-hydroxy-4-phenylbutanoate 
• 203806-77-3 (4S,5R)-4-Benzyl-2,2-dimethyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 5-methyl ester 
• 116565-10-7 (2R,3S)-N-(tert-butoxycarbonyl)-3-amino-2-hydroxy-4-phenylbutanoic acid methyl ester 
• 139163-87-4 (2R,3S)-methyl 3-amino-2-hydroxy-4-phenylbutanoate 
• 134458-64-3 (4S,5S)-2,2-dimethyl-3-(tert-butoxycarbonyl)-4-benzyl-5-formyl-1,3-oxazolidine 
• 54966-42-6 ethyl 3-benzylacrylate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 133333-27-4 tert-butyl (1S)-1-[(2S)-5-oxotetrahydrofuran-2-yl]-2-phenylethylcarbamate 
• 72155-50-1 (3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid 

Relevant articles and documents

Application of the asymmetric aminohydroxylation reaction for the syntheses of HIV-protease inhibitor, hydroxyethylene dipeptide isostere and γ-amino acid derivative

An enantioselective synthesis of lactone 1, a precursor to the (2R,4S,5S) hydroxyethylene dipeptide isostere and amino acid AHPPA 2 has been accomplished from the common intermediate 5 employing Sharpless asymmetric aminohydroxylation as the key step.