742109-04-2

Basic information

• Product Name: (2R,3S)-2-Benzyloxy-3-dibenzylamino-4-phenyl-butyric acid
• Synonyms: (2R,3S)-2-Benzyloxy-3-dibenzylamino-4-phenyl-butyric acid
• CAS NO: 742109-04-2
• Molecular Weight: 465.592
• Mol File: 742109-04-2.mol

Chemical Properties

• CAS DataBase Reference: (2R,3S)-2-Benzyloxy-3-dibenzylamino-4-phenyl-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-2-Benzyloxy-3-dibenzylamino-4-phenyl-butyric acid(742109-04-2)
• EPA Substance Registry System: (2R,3S)-2-Benzyloxy-3-dibenzylamino-4-phenyl-butyric acid(742109-04-2)

Safety Data

• Hazardous Substances Data: 742109-04-2(Hazardous Substances Data)

Upstream product

• 139163-87-4 (2R,3S)-methyl 3-amino-2-hydroxy-4-phenylbutanoate 
• 742109-00-8 ethyl (2R,3S)-3-acetylamino-2-hydroxy-4-phenylbutanoate 
• 100-39-0 benzyl bromide 
• 54966-42-6 ethyl 3-benzylacrylate 
• 742109-03-1 (2R,3S)-2-Benzyloxy-3-dibenzylamino-4-phenyl-butyric acid methyl ester 

Downstream Products

• 129029-32-9 (4S,5S)-5-Benzyl-2-oxo-4-hydroxypyrrolidine 
• 742109-05-3 (3R,4S)-3-Benzyloxy-1-diazo-4-dibenzylamino-5-phenyl-pentan-2-one 

Relevant articles and documents

Application of the asymmetric aminohydroxylation reaction for the syntheses of HIV-protease inhibitor, hydroxyethylene dipeptide isostere and γ-amino acid derivative

An enantioselective synthesis of lactone 1, a precursor to the (2R,4S,5S) hydroxyethylene dipeptide isostere and amino acid AHPPA 2 has been accomplished from the common intermediate 5 employing Sharpless asymmetric aminohydroxylation as the key step.