74235-36-2Relevant academic research and scientific papers
MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF
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, (2018/04/20)
A compound and a method thereof are provided. The compound of the invention has formula I shown below. Each variable in formula I and manufacturing method are defined in the specification. The invention also provides a method for treating organ dysfunction.
Total Synthesis of (+)-Medicarpin
Yang, Xiaoming,Zhao, Yu,Hsieh, Min-Tsang,Xin, Guang,Wu, Rong-Tsun,Hsu, Pei-Lun,Horng, Lin-Yea,Sung, Hui-Ching,Cheng, Chien-Hsin,Lee, Kuo-Hsiung
, p. 3284 - 3288 (2018/01/02)
(+)-Medicarpin has been synthesized asymmetrically for the first time in a linear scalable process with an overall yield of 11%. The two chiral centers were constructed in one step via condensation using a chiral oxazolidinone auxiliary. This method will likely accelerate research on medicarpin as an erythropoietin inducer for erythropoietin-deficient diseases.
Synthesis of tetracyclic heterocompounds as selective estrogen receptor modulators. Part 1. Process development for scale-up of 2,5,8-substituted 5,11 -dihydrochromeno[4,3-c]chromene derivatives
Li, Xun,Reuman, Michael,Russell, Ronald K.,Adams, Richard,Ma, Robert,Beish, Sandra,Branum, Shawn,Youells, Scott,Roberts, Jerry,Jain, Nareshkumar,Kanojia, Ramesh,Sui, Zhihua
, p. 414 - 421 (2012/12/31)
Unsymmetrical benzopyranobenzopyran compounds are novel selective estrogen receptor modulators (SERMs). A reproducible and nonchromatographic process was developed to prepare multihundred gram quantities of 5-(4-(2-(piperidin-1-yl) ethoxy)-phenyl)-5,11-di
