1029608-19-2

Upstream product

• 32884-23-4 2-benzyloxy-4-methoxybenzaldehyde 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 20763-19-3 (methoxymethylene)triphenylphosphorane 
• 100-39-0 benzyl bromide 
• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 1196088-61-5 4-methoxy-2-phenoxybenzaldehyde 

Downstream Products

• 1674359-82-0 (-)-6,9-dimethoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3-ol 
• 1029608-28-3 7-(benzyloxy)-3-(2-(benzyloxy)-4-methoxyphenyl)-2-methoxychromane 
• 74235-36-2 2-benzyloxyl-4-methoxyphenylacetic acid 

Relevant academic research and scientific papers

MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF

A compound and a method thereof are provided. The compound of the invention has formula I shown below. Each variable in formula I and manufacturing method are defined in the specification. The invention also provides a method for treating organ dysfunction.

Unified total syntheses of (-)-medicarpin, (-)-sophoracarpan a, and (±)-kushecarpin a with some structural revisions

The total syntheses of medicarpin, sophoracarpan A, and kushecarpin A from a common intermediate are achieved by using ortho- and para-quinone methide chemistry. Additionally, the relative stereochemistry of sophoracarpan A and B have been reassigned.

o-Quinone methide based approach to isoflavans: application to the total syntheses of equol, 3′-hydroxyequol and vestitol

A concise strategy is developed for the synthesis of isoflavans employing a Diels-Alder reaction between o-quinone methides and aryl-substituted enol ethers followed by reductive cleavage of the acetal group. The method is extended towards the total syntheses of equol, 3′-hydroxyequol and vestitol.