7425-84-5

Basic information

• Product Name: 4-[2-(4-carboxyphenyl)propan-2-yl]benzoic acid
• Synonyms: 2,2-Bis-(p-carboxyphenyl)-propan;2,2-bis-(p-carboxyphenyl)-propane;4,4-(isopropylidene)-bis(benzoicacid);2,2-Bis-(4-carboxy-phenyl)-propan;2,2-bis(4-carboxyphenyl)propane;4,4'-Isopropyliden-di-benzoesaeure;4,4'-isopropylidene-di-benzoic acid
• CAS NO: 7425-84-5
• Molecular Formula: C₁₇H₁₆O₄
• Molecular Weight: 284.312
• Mol File: 7425-84-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 481.5°Cat760mmHg
• Flash Point: 259.1°C
• Density: 1.248g/cm³
• CAS DataBase Reference: 4-[2-(4-carboxyphenyl)propan-2-yl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4-carboxyphenyl)propan-2-yl]benzoic acid(7425-84-5)
• EPA Substance Registry System: 4-[2-(4-carboxyphenyl)propan-2-yl]benzoic acid(7425-84-5)

Safety Data

• Hazardous Substances Data: 7425-84-5(Hazardous Substances Data)

Usage

General Description

4-[2-(4-carboxyphenyl)propan-2-yl]benzoic acid is a compound with the molecular formula C20H20O4. It is a derivative of benzoic acid, containing a propyl side chain with a carboxyphenyl group attached. This chemical compound has potential applications in the pharmaceutical industry, as it may be used in the synthesis of drugs or as a precursor for the production of other organic compounds. Its specific properties and uses will depend on the research and development carried out on this compound in the future.

Synthetic route

2,2-bis(4-cyanophenyl)propane (1675-70-3) → 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5)

Conditions	Yield
With sulfuric acid
With sulfuric acid

2,2-bis-(4-acetyl-phenyl)-propane (16873-39-5) → 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5)

Conditions	Yield
With 1,4-dioxane; sodium hypochlorite
With 1,4-dioxane; sodium hypochlorite

2,2-dichloropropane (594-20-7) + toluene (108-88-3) → 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5) + 3,3'-isopropylidene-di-benzoic acid (22452-69-3)

Conditions	Yield
With aluminium trichloride anschliessend Oxidation mit wss. HNO3;
With aluminium trichloride anschliessend Oxidation mit wss. HNO3;

4,4'-(propane-2,2-diyl)bis(methylbenzene) (1823-31-0) → 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5)

Conditions	Yield
With chromium(VI) oxide
With copper diacetate; oxygen

2,2-dichloropropane (594-20-7) + toluene (108-88-3) → 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5) + 2,2-bis-<3-carboxy-phenyl>-propane(?)

Conditions	Yield
With aluminium trichloride anschliessend Oxidation mit wss. HNO3;
With aluminium trichloride anschliessend Oxidation mit wss. HNO3;

2,2-diphenylpropane (778-22-3) → 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5)

Conditions	Yield
Multi-step reaction with 2 steps 1: AlCl3 2: aqueous NaClO; dioxane View Scheme

1-methyl-4-isopropenylbenzene (1195-32-0) → 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5)

Conditions	Yield
Multi-step reaction with 2 steps 1: (i) HCl, (ii) /BRN= 635760/, AlCl3, MeNO2 2: O2, Cu(OAc)2 View Scheme

toluene (108-88-3) → 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5)

Conditions	Yield
Multi-step reaction with 2 steps 1: (i) HCl, (ii) /BRN= 635760/, AlCl3, MeNO2 2: O2, Cu(OAc)2 View Scheme

methanol (67-56-1) + 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5) → 4,4'-isopropylidene-di-benzoic acid dimethyl ester (34454-33-6)

Conditions	Yield
With hydrogenchloride
With sulfuric acid
With hydrogenchloride

4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5) → (propane-2,2-diylbis(4,1-phenylene))dimethanol (84619-78-3)

Conditions	Yield
Multi-step reaction with 2 steps 1: HCl 2: LiAlH4 View Scheme
Multi-step reaction with 2 steps 1: hydrogenchloride 2: lithium aluminium tetrahydride View Scheme

4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5) → 2,2-Bis-(4-chlorocarbonylphenyl)-propane (19855-84-6)

Conditions	Yield
With pyridine

1,10-Phenanthroline (66-71-7) + 4,4-(isopropylidene)-bis(benzoicacid) (7425-84-5) + zinc(II) acetate dihydrate (5970-45-6) → Zn(2+)*C17H14O4(2-)*C12H8N2 (1480366-58-2)

Conditions	Yield
In water at 160℃; for 96h;

Upstream product

• 1675-70-3 2,2-bis(4-cyanophenyl)propane 
• 594-20-7 2,2-dichloropropane 
• 108-88-3 toluene 
• 1195-32-0 1-methyl-4-isopropenylbenzene 
• 778-22-3 2,2-diphenylpropane 
• 1823-31-0 4,4'-(propane-2,2-diyl)bis(methylbenzene) 
• 16873-39-5 2,2-bis-(4-acetyl-phenyl)-propane 

Downstream Products

• 1480366-58-2 Zn⁽²⁺⁾*C₁₇H₁₄O₄^(2-)*C₁₂H₈N₂ 
• 19855-84-6 2,2-Bis-(4-chlorocarbonylphenyl)-propane 
• 84619-78-3 (propane-2,2-diylbis(4,1-phenylene))dimethanol 
• 34454-33-6 4,4'-isopropylidene-di-benzoic acid dimethyl ester