74262-33-2

Basic information

• Product Name: α-p-phenetidino-isobutyric acid p-phenetidide
• Synonyms: α-p-phenetidino-isobutyric acid p-phenetidide
• CAS NO: 74262-33-2
• Molecular Weight: 342.438
• Mol File: 74262-33-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-p-phenetidino-isobutyric acid p-phenetidide(CAS DataBase Reference)
• NIST Chemistry Reference: α-p-phenetidino-isobutyric acid p-phenetidide(74262-33-2)
• EPA Substance Registry System: α-p-phenetidino-isobutyric acid p-phenetidide(74262-33-2)

Safety Data

• Hazardous Substances Data: 74262-33-2(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 156-43-4 4-Ethoxyaniline 
• 67-64-1 acetone 
• 57-15-8 1,1,1-trichloro-2-methyl-2-propanol 

Relevant articles and documents

Hindered Amines. Synthesis of Hindered Acyclic α-Aminoacetamides

Hindered amines and their nitroxyl radicals are useful in spin-label studies as nonnucleophilic bases and as stabilizers for polymers against UV degradation.Hindered acyclic α-aminoacetamides (3, R5 = aryl, tert-butyl; R6 = H) can be synthesized from amines, ketones, and chloroform with 50percent sodium hydroxide solution in phase-transfer-catalyzed reactions.Nucleophilic secondary amines will undergo the same reactions while bulky ones fail.Mixed 3 can be prepared from different amines according to their nucleophilicities. 1,1-Dialkyl-2,2-dichlorooxirane (5) is believedto be the reactive intermediate.Imines are sometimes formed as byproducts through the opening of a carbon-carbon bond in the oxirane ring by amines.Thus, tert-butylcyclohexylamine (7) is obtained in 62percent yield after hydrogenation of the crude imine from tert-butylamine, cyclohexanone, and chloroform.