742699-20-3

Upstream product

• 56041-85-1 4-ethynylthioanisole 
• 100-52-7 benzaldehyde 
• 124153-81-7 2-methyl-4-[4-(methylsulfanyl)phenyl]-3-butyn-2-ol 
• 104-95-0 (4-bromophenyl)thioanisole 

Downstream Products

• 742699-34-9 3-(4-methylsulfanylphenyl)-1-phenylprop-2-yn-1-one 
• 742699-92-9 3-[4-(methylsulfonyl)phenyl]-1-phenylprop-2-yn-1-one 
• 742699-51-0 4-(4-methylsulfanylphenyl)-3,6-diphenylpyran-2-one 

Relevant academic research and scientific papers

Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: Dual inhibitors of cyclooxygenases and lipoxygenases

A group of 1,3-diarylprop-2-yn-1-ones (13, 17, 23, 26 and 27) possessing a C-3 p-SO2Me COX-2 pharmacophore were designed, synthesized and evaluated as potential dual inhibitors of cyclooxygenase-1/2 (COX-1/2) and 5/15-lipoxygenases (5/15-LOX) t

Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases

A new class of 1,3-diphenylprop-2-yn-1-ones possessing a p-MeSO2 COX-2 phamacophore on the C-3 phenyl ring was designed for evaluation as dual inhibitors of cyclooxygenase (COX) and lipoxygenase (LOX). Among the group of compounds evaluated, 1-

Design, synthesis, and structure-activity relationship studies of 3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 inhibitors

A group of regioisomeric 3,4,6-triphenylpyran-2-ones with a MeSO 2 pharmacophore at the paraposition of either a C-3 phenyl or a C-4 phenyl substituent on the central six-membered pyran-2-one ring were prepared and evaluated in vitro for their