74328-44-2

Basic information

• Product Name: 4-methyl-2-p-tolylsulphonyl-2,3-dihydro-1,2-benzothiazepin-5(4H)-one
• Synonyms: 4-methyl-2-p-tolylsulphonyl-2,3-dihydro-1,2-benzothiazepin-5(4H)-one
• CAS NO: 74328-44-2
• Molecular Weight: 347.459
• Mol File: 74328-44-2.mol

Chemical Properties

• CAS DataBase Reference: 4-methyl-2-p-tolylsulphonyl-2,3-dihydro-1,2-benzothiazepin-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-p-tolylsulphonyl-2,3-dihydro-1,2-benzothiazepin-5(4H)-one(74328-44-2)
• EPA Substance Registry System: 4-methyl-2-p-tolylsulphonyl-2,3-dihydro-1,2-benzothiazepin-5(4H)-one(74328-44-2)

Safety Data

• Hazardous Substances Data: 74328-44-2(Hazardous Substances Data)

Upstream product

• 771-17-5 3-methyl-2,3-dihydro-4H-thiochromen-4-one 
• 127-65-1 chloroamine-T 
• 76664-73-8 4-Methyl-N-[2-(2-methyl-acryloyl)-phenylsulfanyl]-benzenesulfonamide 
• 74328-45-3 2,2-dimethylbenzothiophen-3(2H)-one 
• 74328-43-1 3-methyl-1-(p-tolylsulphonylimino)thiochroman-4-one 
• 74328-46-4 2,2-dimethyl-1-p-tolylsulphonyliminobenzothiophen-3(2H)-one 

Downstream Products

• 76664-74-9 4-methyl-5-oxo-2-p-tolylsulphonyl-2,3,4,5-tetrahydro-1,2-benzothiazepine 1-oxide 
• 76664-75-0 4-methyl-5-oxo-2-p-tolylsulphonyl-2,3,4,5-tetrahydro-1,2-benzothiazepine 1,1-dioxide 

Relevant articles and documents

Conversions of Thiochroman-4-ones into 1,2-Benzothiazepine, Benzothiophen, and 1,2-Benzisothiazole Systems via Sulphimide Intermediates

Reaction of thiochroman-4-ones (1a-g) with chloramine-T gave the corresponding N-tosylsulphimides (2a-g) and sulphoxides (5a-g).The N-tosylsulphimides (2a-d), on reaction with triethylamine in chloroform, gave 2-tosyl-2,3-dihydro-1,2-benzothiazepin-5(4H)-

Novel Conversions of Benzothiophen-3(2H)-ones into 1,2-Benzisothiasole and Tetrahydro-1,2-benzothiazepin-5-one Systems via Sulphimide Intermediates

S-Amination of 2,2-dimethyl- (3a) and 2-benzyl-2-methyl-benzothiophen-3(2H)-one (3b) with O-mesitylenesulphonylhydroxylamine followed by treatment with base yielded 3-isopropenyl- (4a) and 3-(1-benzylvinyl)-1,2-benzisothiazole (4b), respectively.Simila

SULFILIMINES IN ORGANIC SYNTHESES: NEW ENTRIES INTO TETRAHYDRO-1,2-BENZOTHIAZEPINE AND 1,2-BENZISOTHIAZOLE SYSTEMS

Novel ring transformations of thiochroman-4-ones and benzothiophen-3(2H)-ones to tetrahydro-1,2-benzothiazepin-5-ones and 1,2-benzisothiazoles via sulfilimine intermediates are described.