74334-74-0

Upstream product

• 73654-59-8 1,2,4-tri-O-acetyl-3-O-benzyl-α,β-D-xylopyranose 
• 67-56-1 methanol 
• 73654-70-3 Acetic acid (3R,4S,5R)-5-acetoxy-4-benzyloxy-2-bromo-tetrahydro-pyran-3-yl ester 

Downstream Products

• 1432612-86-6 methyl N,3-O-dibenzyl-2,4-dideoxy-2,4-imino-L-ribonamide 
• 72521-39-2 methyl 3-O-benzyl-β-D-xylopyranoside 
• 1432612-81-1 C₁₉H₂₁NO₃ 
• 1432612-79-7 methyl 3-O-benzyl-2,4-di-O-trifluoromethanesulfonyl-β-D-xylopyranoside 
• 1432612-80-0 methyl N,3-O-dibenzyl-2,4-dideoxy-2,4-imino-β-L-ribopyranoside 
• 1432612-82-2 methyl N,3-O-dibenzyl-2,4-dideoxy-2,4-imino-β-L-ribopyranoside 
• 1432612-84-4 methyl N,3-O-dibenzyl-2,4-dideoxy-2,4-imino-L-ribonate 
• 1432612-85-5 N,3-O-dibenzyl-2,4-dideoxy-2,4-imino-L-ribonic acid 

Relevant academic research and scientific papers

3-Hydroxyazetidine Carboxylic Acids: Non-Proteinogenic Amino Acids for Medicinal Chemists

The formation from D-glucose of both enantiomers of 2,4-dideoxy-2,4-iminoribonic acid is the first chemical synthesis of unprotected 3-hydroxyazetidine carboxylic acids. The long-term stability of 3-hydroxyazetidine amides is established at acidic and neutral pH and implies their value as non-proteinogenic amino acid components of peptides, providing medicinal chemists with a new class of peptide isosteres. The structure of N,3-O-dibenzyl-2,4-dideoxy-2,4-imino-D-ribonic acid was established by X-ray crystallographic analysis. An N-methylazetidine amide derivative is a specific inhibitor of β-hexosaminidases at the micromolar level, and is only the second example of potent inhibition of any glycosidase by an amide of a sugar amino acid related to an iminosugar.