74338-92-4

Upstream product

• 74338-75-3 2-cyanoethyl(phenyl)sulfoxide 
• 106-96-7 propargyl bromide 
• 108-98-5 thiophenol 
• 3055-87-6 3-(phenylthio)propionitrile 
• 63067-91-4 3-hydroxy-2-phenylsulphinylprop-1-ene 
• 123533-73-3 2-phenylsulphinyl-3-p-toluenesulphonyloxyprop-1-ene 

Downstream Products

• 138689-92-6 phenyl isopropenyl sulfoxide 
• 123533-83-5 N-p-tolyl-3-ethoxycarbonyl-5-phenylsulphinyl-3,4,5,6-tetrahydro-2(1H)-pyridone 
• 123533-76-6 N-p-tolyl-N-(2-phenylsulphinylprop-2-enyl)amine 
• 63067-91-4 3-hydroxy-2-phenylsulphinylprop-1-ene 
• 79496-93-8 2,3-bis(phenylsulphinyl)prop-1-ene 
• 74338-79-7 C₁₄H₁₂O₂S₂ 
• 139371-09-8 4-methoxy-2-(2-phenylsulfinyl-2-propenyl)phenyl 2-phenylsulfinyl-2-propyl ether 

Relevant academic research and scientific papers

3-PHENOXY-2-PHENYLSULPHINYLPROP-1-ENE AND 3-BROMO-2-PHENYLSULPHINYLPROP-1-ENE, SYNTHONS FOR N-ALKYLATED CYCLIC ENAMIDES.

2-Alkyl(and aryl)amino-2-phenylsulphinylprop-1-enes (derived from benzylamine, cyclohexylamine, and p-toluidine), underwent conjugate addition with diethyl sodiomalonate to give adducts which cyclised to give N-alkylated lactams.Thermolysis of the lactams results in regioselective elimination of benzenesulphenic acid to give N-alkylated cyclic enamides in good yields.The 3-alkyl(and aryl)amino-2-phenylsulphinylprop-1-enes were conveniently prepared by the addition of benzenesulphenic acid to 3-alkyl(and aryl)aminoprop-1-ynes, and by reaction of 3-bromo- and 3-phenoxy-2-phenylsulphinylprop-1-ene with the appropriate amine.

Synthesis of Alkenyl Sulphoxides by Intramolecular and Intermolecular Addition of Sulphenic Acids to Alkynes

Alkyne-ω-sulphenic acids formed by thermolysis of ω-(t-butylsulphinyl)alkynes at 40 deg C cyclized regiospecifically to 2-methylenethiacycloalkane 1-oxides; 2-methylenethietan 1-oxide was not formed in this way. 2-Methylpropane-2-sulphenic acid, obtained by heating di-t-butyl sulphoxide, added regioselectively to oct-1-yne to give predominantly 2-t-butylsulphinyloct-1-ene, which itself decomposed thermally to a mixture of dioctenyl sulphoxides by way of alkenesulphenic acid-dialkyl sulphine interconversions.Benzenesulphenic acid, methanesulphenic acid, and ethoxycarbonylmethanesulphenic acid, conveniently generated by thermolysis of 1-cyano-2-alkyl(or aryl)sulphinylethanes, underwent intermolecular addition to unactivated and activated alkynes regioselectively to give alkenyl sulphoxides in good yields.