743476-80-4Relevant academic research and scientific papers
Antiviral agents
-
, (2008/12/05)
This invention relates to a compound capable of binding to a picornavirus capsid comprising two or more capsid binding moieties.
Synthesis and antiviral activity of dimeric capsid-binding inhibitors of human rhinovirus (HRV)
Krippner, Guy Y.,Chalmers, David K.,Stanislawski, Pauline C.,Tucker, Simon P.,Watson, Keith G.
, p. 553 - 564 (2007/10/03)
A set of dimeric analogues of known rhinovirus capsid-binders Pleconaril 1 and Pirodavir 55 has been synthesized and tested against two representative human rhinovirus (HRV) strains. Dimers with linker lengths ranging from five atoms up to approximately 6
