74357-14-5Relevant academic research and scientific papers
Selective aerobic oxidative dibromination of alkenes with aqueous HBr and sodium nitrite as a catalyst
Podgorsek, Ajda,Eissen, Marco,Fleckenstein, Jens,Stavber, Stojan,Zupan, Marko,Iskra, Jernej
scheme or table, p. 120 - 126 (2010/04/22)
Various alkenes (internal, terminal, aryl and alkyl substituted) and 1,2-diphenylethyne were efficiently and selectively dibrominated using 2 equivalents of 48% aqueous hydrobromic acid, with air as an oxidant and sodium nitrite as a catalyst. Despite the presence of water, only trans dibromination occurred producing anti-1,2-dibromoalkanes and (E)-1,2-dibromo-1,2- diphenylethene. A comparison of resource demand, waste production and environmental, health and safety issues of the NaNO2 catalyzed aerobic bromination with molecular bromine and other oxidative bromination methods revealed that the proposed method is not only selective and effective but has a better environmental profile.
InX3-catalyzed haloamidation of vinyl arenes: a facile synthesis of α-bromo- and α-fluoroamides
Yadav,Subba Reddy,Narasimha Chary,Chandrakanth
scheme or table, p. 1136 - 1138 (2009/05/11)
A variety of alkenes are converted into the corresponding α-fluoroamides in high yields by selectfluorTM in the presence of 10 mol % of InF3 in nitrile solution. α-Bromoamides are obtained with NBS in the presence of 10 mol % InBr3 under similar conditions. The use of Lewis acid in haloamidation significantly improved the yields and reaction rates.
