74392-86-2Relevant academic research and scientific papers
5(4H)-oxazolones as intermediates in the carbodiimide- and cyanamide-promoted peptide activations in aqueous solution
Danger, Grégoire,Michaut, Arthur,Bucchi, Manon,Boiteau, Laurent,Canal, Justine,Plasson, Rapha?l,Pascal, Robert
supporting information, p. 611 - 614 (2013/02/23)
The early days: Although considered a species to be avoided in peptide chemistry, the intermediacy of 5(4H)-oxazolones is demonstrated to be essential for the formation of peptides through cyanamide and carbodiimide activation in aqueous solution (see sch
Amphiphilic dendritic dipeptides and their self-assembly into helical pores
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Page/Page column 67, (2008/06/13)
An amphiphilic dendritic dipeptide, comprises a dipeptide(s) comprising one or more of a naturally occurring or synthetic amino acids and a dendron. These are suitable for use in various formulations, films, coatings, membranes and sensors, among other ap
Evidence of the Preferential Involvement of μ Receptors in Analgesia Using Enkephalins Highly Selective for Peripheral μ or δ Receptors
Gacel, Gilles,Fournie-Zaluski, Marie-Claude,Fellion, Etienne,Roques, Bernard P.
, p. 1119 - 1124 (2007/10/02)
In order to study the preferential involvement of μ or δ receptors in the analgesic effects of enkephalins, several peptides which selectively interact with these two kinds of receptors in peripheral organs were synthesized.The inhibitory potency on the e
Synthesis and pharmacological study of some enkephalin analogs in relation to the plurality of opiate receptors
Audigier,Mazarguil,Gout,Cros
, p. 173 - 177 (2007/10/02)
We have synthesized a series of enkephalin analogs and measured their affinity for each type of 'opiate' receptor, the μ receptor and the δ receptor. Furthermore, we have determined their respective antinociceptive activity after intracerebroventricular i
