74392-85-1

Basic information

• Product Name: L-Leucinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-tyrosyl-D-alanylglycyl-L-phenylalanyl-
• CAS NO: 74392-85-1
• Molecular Formula: C34H48N6O8
• Molecular Weight: 668.791
• Mol File: 74392-85-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Leucinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-tyrosyl-D-alanylglycyl-L-phenylalanyl-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-tyrosyl-D-alanylglycyl-L-phenylalanyl-(74392-85-1)
• EPA Substance Registry System: L-Leucinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-tyrosyl-D-alanylglycyl-L-phenylalanyl-(74392-85-1)

Safety Data

• Hazardous Substances Data: 74392-85-1(Hazardous Substances Data)

Upstream product

• 74825-83-5 Boc-(L)(α-Me)Tyr-OH 
• 66444-26-6 Methyl tert-butyloxycarbonyltyrosyl-(D)alanylglycylphenylalaninate 
• 67582-10-9 Boc Tyr D_.Ala Gly Phe OH 
• 78537-07-2 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycine methyl ester 
• 74392-86-2 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanine methyl ester 
• 64410-47-5 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycine 
• 71591-34-9 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanine 
• 687-51-4 H-L-Leu-NH₂ 
• 74392-87-3 Boc Tyr D_.Ala Gly Phe Leu OMe 

Downstream Products

• 65189-64-2 H-Tyr-D-Ala-Gly-Phe-Leu-NH₂ 

Relevant articles and documents

Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides

Previously, our laboratory showed that the oxymethyl-modified coumarinic acid (OMCA) cyclic prodrug of the opioid peptide DADLE ([D-Ala 2,D-Leu5]-Enk, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH) exhibited low permeation across both the intestinal