67582-10-9

Upstream product

• 959785-78-5 Boc-Tyr-D-Ala-Gly-Phe-OEt 
• 71591-34-9 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanine 
• 3978-80-1 Boc-Tyr-OH 
• 63-91-2 L-phenylalanine 
• 64410-47-5 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycine 
• 74825-83-5 Boc-(L)(α-Me)Tyr-OH 
• 78537-07-2 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycine methyl ester 
• 74392-86-2 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanine methyl ester 
• 66444-26-6 Methyl tert-butyloxycarbonyltyrosyl-(D)alanylglycylphenylalaninate 

Downstream Products

• 74392-87-3 Boc Tyr D_.Ala Gly Phe Leu OMe 
• 67581-53-7 N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycyl-L-phenylalanyl-L-methionine methyl ester 
• 74392-85-1 Boc Tyr D_.Ala Gly Phe Leu NH₂ 
• 65189-64-2 H-Tyr-D-Ala-Gly-Phe-Leu-NH₂ 
• 61090-95-7 (S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyramide 
• 66864-07-1 Tyr D_.Ala Gly Phe Pro NH₂ 
• 66960-03-0 Boc Tyr D_.Ala Gly Phe Met NH₂ 
• 66444-27-7 Boc-L-Tyr-D-Ala-Gly-L-PheNHNH₂ 

Relevant academic research and scientific papers

Hydrazone linker as a useful tool for preparing chimeric peptide/ Nonpeptide bifunctional compounds

The area of multitarget compounds, joining two pharmacophores within one molecule, is a vivid field of research in medicinal chemistry. Not only pharmacophoric elements are essential for the design and activity of such compounds, but the type and length o

Development of novel enkephalin analogues that have enhanced opioid activities at both μ and δ opioid receptors

Enkephalin analogues with a 4-anilidopiperidine scaffold have been designed and synthesized to achieve therapeutic benefit for the treatment of pain due to mixed μ and δ opioid agonist activities. Ligand 16, in which a Dmt-substituted enkephalin-like stru

Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides

Previously, our laboratory showed that the oxymethyl-modified coumarinic acid (OMCA) cyclic prodrug of the opioid peptide DADLE ([D-Ala 2,D-Leu5]-Enk, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH) exhibited low permeation across both the intestinal

Synthesis and pharmacological study of some enkephalin analogs in relation to the plurality of opiate receptors

We have synthesized a series of enkephalin analogs and measured their affinity for each type of 'opiate' receptor, the μ receptor and the δ receptor. Furthermore, we have determined their respective antinociceptive activity after intracerebroventricular i