74415-18-2

Upstream product

• 304479-42-3 3-(2-nitro-benzoylhydrazono)-butyric acid ethyl ester 
• 610-14-0 2-nitrobenzyl chloride 
• 606-27-9 methyl 2-nitrobenzoate 
• 606-26-8 o-nitrobenzohydrazide 

Downstream Products

• 43100-30-7 1,2-Bis(2-aminobenzoyl)hydrazine 
• 74415-22-8 2,5-bis(2-nitrophenyl)-1,3,4-oxadiazole 
• 552-16-9 ortho-nitrobenzoic acid 
• 302-01-2 hydrazine 
• 19542-04-2 2-[5-(2-aminophenyl)-(1,3,4-oxadiazol-2-yl)]-benzenamine 
• 88518-07-4 2,2'-[1,3,4]thiadiazole-2,5-diyl-bis-aniline 
• 1456-21-9 diphenyl-[1,3,4]thiadiazole 
• 725-12-2 2,5-bis-(phenyl)-1,3,4-oxadiazole 
• 106269-38-9 2,5-bis-(2-nitro-phenyl)-[1,3,4]thiadiazole 

Relevant academic research and scientific papers

An Efficient Oxidation of Acid Hydrazides to N,N′-Diacylhydrazines Using Copper(II) Acetate in Solvent-Free Conditions Under Microwave Irradiation

A simple and efficient method for solvent free "dry" state transformation of acid hydrazides 1 to corresponding N,N′ -diacylhydrazines 2 using copper(II) acetate under microwave irradiation has been described. The products are obtained in good yields and excellent purities.

A convenient and simple transformation of acid hydrazides to N,N′-diacylhydrazines with Hg(OAc)2 under solid state conditions

A highly efficient and practical methodology for the transformation of acid hydrazides 1 to N,N′-diacylhydrazines 2 is described under solid state conditions at RT utilizing inexpensive and easily available reagent Hg(OAc) 2. The products are obtained in good yields with high purity.

Some hypervalent iodine(III) mediated solid-state transformations

Some known hypervalent iodine(III) mediated reactions, viz (i) dimerization of acid hydrazides 1a-i, (ii) α-tosyloxylation of acetophenones 3a-f, and (iii) α-hydroxylation of acetophenones 3c,d,f have been effected in solid-state.

Hypervalent iodine oxidation of acid hydrazides: A new synthesis of N,N'-diacylhydrazines

Hypervalent iodine oxidation of p-substituted benzohydrazides (1a-h), phenylacetohydrazide (1i) and heterocyclic acid hydrazides (1j-l) using one equivalent of iodobenzene diacetate in dry dichloromethane or acetonitrile leads to dimerization thereby providing a new and facile method for the synthesis of N,N-diacylhydrazines 2.

1,2,3-benzotriazinone 1-oxides

3-Substituted 1,2,3-benzotriazin-4(3H)-one 1-oxides are formed on peracid oxidation of 3-alkyl- and 3-methoxy-1,2,3-benzotriazin-4(3H)-ones. The 3-(a-alkoxyalkyl) 1-oxide derivatives could be dealkylated to the tautomeric 3-unsubstituted compound. The acidities of the isomeric N-oxides of the 1,2,3-benzotriazinone system are compared. Phenyl iodosodiacetate converts o-nitrobenzaldehyde benzyl- and phenyl-hydrazones into the 2-substituted 4-oxido-1,2,3-benzotriazine1 -oxide betaines(1).

Substitution Reactions of Phenylated Aza-heterocycles. Part 1. Nitration of 2,5-Diphenyl-1,3,4-oxadiazole: a Product Study using High Performance Liquid Chromatography

Contrary to a previous literature report, nitration of 2,5-diphenyl-1,3,4-oxadiazole (1) under various conditions gives a mixture of all six possible 2,5-bisnitrophenyl derivatives, which may be analysed quantitatively using high performance liquid chromatography.Nitration using nitric acid alone gives mainly the three isomers with p-nitrophenyl groups, i.e. (7), (9), and (10), whereas mixed acids and nitronium tetrafluoroborate give mainly meta-nitration products, i.e. (6), (8), and (9).Nitration of the three 2-(nitrophenyl)-5-phenyl-1,3,4-oxadiazoles also shows considerable variation of product ratio according to the conditions.