1456-21-9

Basic information

• Product Name: 2,5-Diphenyl-1,3,4-thiadiazole
• Synonyms: 2,5-Diphenyl-1,3,4-thiadiazole
• CAS NO: 1456-21-9
• Molecular Formula: C₁₄H₁₀N₂S
• Molecular Weight: 238.3076
• Mol File: 1456-21-9.mol
• Article Data: 40

Chemical Properties

• Melting Point: 94-95 °C
• Boiling Point: 403.1°C at 760 mmHg
• Flash Point: 189.2°C
• Appearance: /
• Density: 1.216g/cm³
• Vapor Pressure: 2.44E-06mmHg at 25°C
• Refractive Index: 1.633
• PKA: -0.44±0.10(Predicted)
• CAS DataBase Reference: 2,5-Diphenyl-1,3,4-thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Diphenyl-1,3,4-thiadiazole(1456-21-9)
• EPA Substance Registry System: 2,5-Diphenyl-1,3,4-thiadiazole(1456-21-9)

Safety Data

• Hazardous Substances Data: 1456-21-9(Hazardous Substances Data)

Usage

General Description

2,5-Diphenyl-1,3,4-thiadiazole is a chemical compound with the molecular formula C14H10N2S. It is a heterocyclic compound containing a thiadiazole ring and two phenyl groups. 2,5-Diphenyl-1,3,4-thiadiazole has been studied for its potential use in materials science, particularly as a fluorescent probe and as a component in organic light-emitting diodes (OLEDs). It has also shown promise as a building block for the synthesis of larger molecules with potential applications in pharmaceuticals, agrochemicals, and other industries. Additionally, 2,5-Diphenyl-1,3,4-thiadiazole has been investigated for its antimicrobial and anticancer properties, making it a versatile and potentially useful chemical compound for various scientific and industrial applications.

InChI:InChI=1/C14H10N2S/c1-3-7-11(8-4-1)13-15-16-14(17-13)12-9-5-2-6-10-12/h1-10H

Upstream product

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• 5199-89-3 benzoylformic acid (N-benzoyl)hydrazone 
• 100-52-7 benzaldehyde 

Downstream Products

• 52143-03-0 3-ethyl-2,5-diphenyl-[1,3,4]thiadiazolium; toluene-4-sulfonate 
• 52143-05-2 3-methyl-2,5-diphenyl-[1,3,4]thiadiazolium; toluene-4-sulfonate 

Relevant articles and documents

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Synthesis of 1,3,4-thiadiazoles from aldehyde hydrazones

Reaction of p-tolualdehyde hydrazone with disulfur dichloride in the presence of DBU gave 2,5-di (p-tolyl)-1,3,4-thiadiazole (1a) in 54% yield. Phenyldiazomethane also reacted with disulfur dichloride to afford 2,5-diphenyl-1,3,4-thiadiazole (1b) in 80% y

Synthesis of substituted 1,3,4-thiadiazoles using Lawesson's reagent

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Preparation method of 1, 3, 4-thiadiazole compound and compound prepared by preparation method

The invention belongs to the field of medicinal chemistry. Specifically, the invention discloses a preparation method of a 1, 3, 4-thiadiazole compound and the compound prepared by using the preparation method. According to the method, the 1, 3, 4-thiadia

A KHSO4 promoted tandem synthesis of 1,3,4-thiadiazoles from thiohydrazides and DMF derivatives

An efficient, simple and environmentally benign method for the construction of 1,3,4-thiadiazole skeletons via the tandem coupling and cyclization of thiohydrazides with DMF derivatives in the presence of KHSO4 has been reported. This method re