744209-07-2Relevant academic research and scientific papers
Synthesis and biological characterization of novel hybrid 7-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro- naphthalen-2-ol and their heterocyclic bioisosteric analogues for dopamine D2 and D3 receptors
Dutta, Aloke K.,Venkataraman, Sylesh K.,Fei, Xiang-Shu,Kolhatkar, Rohit,Zhang, Shijun,Reith, Maarten E.A.
, p. 4361 - 4373 (2007/10/03)
In a recent preliminary communication we described the development of a series of hybrid molecules for the dopamine D2 and D3 receptor subtypes. The design of these compounds was based on combining pharmacophoric elements of aminotetralin and piperazine m
