74447-34-0Relevant articles and documents
HBED-NN: A Bifunctional Chelator for Constructing Radiopharmaceuticals
Makarem, Ata,Klika, Karel D.,Litau, German,Remde, Yvonne,Kopka, Klaus
, p. 7501 - 7508 (2019)
Radiometal-based radiopharmaceuticals bearing bifunctional HBED chelators are powerful radiotracers for cancer diagnosis and therapy. Bifunctional HBED chelators make strong complexes with trivalent gallium and are able to bind to bioactive molecules thro
DNAzymes for amine and peptide lysine acylation
Yao, Tianjiong,Przybyla, Jack J.,Yeh, Peter,Woodard, Austin M.,Nilsson, Hannah J.,Brandsen, Benjamin M.,Silverman, Scott K.
supporting information, p. 171 - 181 (2021/01/18)
DNAzymes were previously identified by in vitro selection for a variety of chemical reactions, including several biologically relevant peptide modifications. However, finding DNAzymes for peptide lysine acylation is a substantial challenge. By using suita
CYCLIC COMPOUNDS AND METHODS OF MAKING AND USING
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Page/Page column 109; 111, (2020/10/19)
Disclosed are compounds and methods for highly effective chemoselective peptide cyclization and bicyclization directly on unprotected peptides and other compounds as well as the compounds produced by the methods, which have a novel structural motif. The fast reaction rate and operational simplicity render this method to be highly effective to synthesize cyclic structures, i.e. cyclic peptides. The cyclic compounds allow for various functionalities useful in chemical biology study and drug discovery.
