74470-40-9Relevant articles and documents
MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS
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, (2018/03/25)
The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describes the preparation, pharmaceutical composition and the use of compound formula (I).
CARBINOL DERIVATIVES HAVING CYCLIC LINKER
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Page/Page column 25, (2010/03/31)
[Object] To provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease. [Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate.
Synthesis of pyridone and pyridine rings by [4+2] hetero-cyclocondensation
Robin, Aélig,Julienne, Karine,Meslin, Jean Claude,Deniaud, David
, p. 9557 - 9559 (2007/10/03)
Substituted pyridones and pyridines have been synthesised efficiently by employing iminium salt as a key precursor. These compounds were prepared using tandem [4+2] cycloaddition/deamination between azabutadiene and dienophiles.
