74476-53-2 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
Ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate is utilized as a building block for the synthesis of bioactive molecules, contributing to the advancement of new pharmaceutical agents.
Used in Anti-inflammatory Applications:
In the medical field, Ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate is used as a precursor in the development of anti-inflammatory drugs, potentially aiding in the treatment of various inflammatory conditions.
Used in Antifungal Applications:
Ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate is employed as a starting material for creating antifungal agents, which can be instrumental in combating fungal infections.
Used in Antibacterial Applications:
Ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate is also used in the development of antibacterial drugs, playing a role in the fight against bacterial infections.
Used in Chemical Intermediates for Pharmaceutical and Agrochemical Industries:
Beyond direct medicinal applications, Ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate serves as a chemical intermediate, enabling the production of other functional molecules that are vital in both the pharmaceutical and agrochemical sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 74476-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,4,7 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 74476-53:
(7*7)+(6*4)+(5*4)+(4*7)+(3*6)+(2*5)+(1*3)=152
152 % 10 = 2
So 74476-53-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H11ClN2O2S/c1-2-17-11(16)10-9(15-12(14)18-10)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H2,14,15)
74476-53-2Relevant academic research and scientific papers
Discovery of a new class of protein farnesyltransferase inhibitors in the arylthiophene series
Lethu, Sébastien,Ginisty, Maryon,Bosc, Damien,Dubois, Jo?lle
supporting information; experimental part, p. 6205 - 6208 (2010/03/24)
Screening of the ICSN chemical library led to the discovery of 3-(4-chlorophenyl)-4-cyano-5-thioalkylthiophene 2-carboxylic acids as potent farnesyltransferase inhibitors. Enzymatic kinetic studies showed that this original FTI series belongs to the CaaX
Syntheses and Reactions of 2-Halo-5-thiazolecarboxylates
Lee, Len F.,Schleppnik, Francis M.,Howe, Robert K.
, p. 1621 - 1630 (2007/10/02)
A variety of 2-halo-5-thiazolecarboxylates was prepared from substituted-3-aminoacrylates and 3-ketoesters.Selective reduction of 2-chloro-5-thiazolecarboxylates 4a, 4i and 4j with sodium borohydride in ethanol provided the corresponding 2-halo-5-thiazolemethanols 27 - 29.Nucleophilic displacement on methyl methanesulfonate (32c) occured selectivity at the 5-substituent to provide 2-chloro-4-(trifluoromethyl)-5-(heteroatom-substituted methyl)thiazoles 32d-f.
2-Amino-4-substituted-thiazolecarboxylic acids and their derivatives
-
, (2008/06/13)
2-Amino-4-substituted-5-thiazolecarboxylic acids and derivatives thereof, are intermediates for the preparation of 2-substituted-4-substituted-5-thiazolecarboxylic acid derivatives which are herbicidal safeners.
