74476-53-2 Usage
General Description
Ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate is an organic compound with the chemical formula C12H11ClN2O2S. It is a thiazole derivative, which is a five-membered heterocyclic compound containing a sulfur and nitrogen atom in the ring. Ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate is commonly used in pharmaceutical research and drug development as a building block for the synthesis of various bioactive molecules. It has potential applications in the development of anti-inflammatory, antifungal, and antibacterial drugs due to its structural properties and biological activities. Additionally, it can be used as a chemical intermediate for the production of other functional molecules in the pharmaceutical and agrochemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 74476-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,4,7 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 74476-53:
(7*7)+(6*4)+(5*4)+(4*7)+(3*6)+(2*5)+(1*3)=152
152 % 10 = 2
So 74476-53-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H11ClN2O2S/c1-2-17-11(16)10-9(15-12(14)18-10)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H2,14,15)
74476-53-2Relevant articles and documents
Discovery of a new class of protein farnesyltransferase inhibitors in the arylthiophene series
Lethu, Sébastien,Ginisty, Maryon,Bosc, Damien,Dubois, Jo?lle
supporting information; experimental part, p. 6205 - 6208 (2010/03/24)
Screening of the ICSN chemical library led to the discovery of 3-(4-chlorophenyl)-4-cyano-5-thioalkylthiophene 2-carboxylic acids as potent farnesyltransferase inhibitors. Enzymatic kinetic studies showed that this original FTI series belongs to the CaaX
2-Amino-4-substituted-thiazolecarboxylic acids and their derivatives
-
, (2008/06/13)
2-Amino-4-substituted-5-thiazolecarboxylic acids and derivatives thereof, are intermediates for the preparation of 2-substituted-4-substituted-5-thiazolecarboxylic acid derivatives which are herbicidal safeners.
