74491-55-7

Basic information

• Product Name: Acetamide, N-[2-(phenylthio)cyclohexyl]-, trans-
• CAS NO: 74491-55-7
• Molecular Formula: C14H19NOS
• Molecular Weight: 249.377
• Mol File: 74491-55-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[2-(phenylthio)cyclohexyl]-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2-(phenylthio)cyclohexyl]-, trans-(74491-55-7)
• EPA Substance Registry System: Acetamide, N-[2-(phenylthio)cyclohexyl]-, trans-(74491-55-7)

Safety Data

• Hazardous Substances Data: 74491-55-7(Hazardous Substances Data)

Upstream product

• 4837-31-4 4-Phenylsulfanyl-morpholine 
• 75-05-8 acetonitrile 
• 110-83-8 cyclohexene 
• 931-59-9 benzenesulfenyl chloride 
• 64168-52-1 4'-nitrobenzenesulfenanilide 
• 882-33-7 diphenyldisulfane 

Relevant articles and documents

THERMAL REACTIVITY OF 4'SUBSTITUTED- AND 4'-SUBSTITUTED-2-PHENYL-BENZENESUPHENANILIDES

The thermal decomposition of 4'-nitro, 4'-H, and 4'-methoxy-benzenesulphenanilides in benzene and/or furan, and of 4'-substituted-2-phenylbenzenesulphenanilides ( 1d-1f ) in benzene, was found to proceed by two distinct pathways: ( i ) nucleophilic displacement by furan and/or another sulphenanilide unit and ( ii ) homolytic S-N bond fission to give sulphenyl and anilino radicals.An increase in the electron-withdrawning capability of the 4'-substituted favours the ionic pathway, whwreas the radical pathway is favoured by an increase in the reaction temperature.

Additions to Alkenes via Metal Ion-Promoted Oxidation of Dialkyl and Diaryl Disulphides

Reactions of alkenes with di-n-propyl, diphenyl, and dibenzyl disulphide in the presence of lead(IV) salts in trifluoroacetic acid-dichloromethane are described.The products, vicinal trifluoroacetoxysulphides, are obtained in higher yields with manganese(III) salts as the oxidant.Alternative reaction conditions with use of iron(III) salts or in the absence of added metal salts are also described.Trifluoroacetoxysulphides derived from diphenyl disulphide react with acetonitrile under Ritter conditions to give acetamidosulphides but trifluoroacetoxysulphides derived from dibenzyl disulphide only give the vicinal acetamidosulphides in poor yield as a result of an alternative reaction pathway affording benzylacetamide.Conversions of acetamidosulphides into aminosulphides and into acetamidothiols are described.

AMIDINOSULPHENYLATION OF ALKENES

Phenylsulphenamides react chemoselectively with an alkene and a nitrile in the presence of trifluoromethanesulphonic acid to give N-(β-phenylthioalkyl)amidines; in the absence of nitrile an amine is formed.