745072-29-1Relevant academic research and scientific papers
Design and synthesis of novel tetrahydronaphthyl azoles and related cyclohexyl azoles as antileishmanial agents
Marrapu, Vijay K.,Srinivas, Nagarapu,Mittal, Monika,Shakya, Nishi,Gupta, Suman,Bhandari, Kalpana
, p. 1407 - 1410 (2011)
A novel series of trans-2-aryloxy-1,2,3,4,-tetrahydronaphthyl azoles and related cyclohexyl azoles were synthesized and evaluated in vitro against Leishmania donovani. Compound 9 identified as most active analog with IC 50 value of 0.64 μg/mL a
Synthesis of tetrahydronaphthyl thioureas as potent appetite suppressants
Bhandari, Kalpana,Srivastava, Shipra,Shankar, Girija
, p. 4189 - 4196 (2007/10/03)
A series of thiourea derivatives (7-23, 25-27) of 1- aminotetrahydronaphthalene (4) and 1-amino-2-hydroxytetrahydronaphthalene (5) were synthesized in single pot in 48-90% yield and evaluated for their anorexigenic activity. Among them compounds 10, 14, 15, 16 and 22 exhibited significant anorexigenic activity without any antidepressant effect and provided a new structural lead for appetite suppressants.
