74570-02-8

Basic information

• Product Name: Phenol,4-[(1,2,3,4,5,6,7,8-octahydro-1-isoquinolinyl)methyl]-
• Synonyms: Phenol,4-[(1,2,3,4,5,6,7,8-octahydro-1-isoquinolinyl)methyl]-, (?à)-
• CAS NO: 74570-02-8
• Molecular Formula: C16H21 N O
• Molecular Weight: 243.349
• Mol File: 74570-02-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 412.9°Cat760mmHg
• Flash Point: 142.3°C
• Density: 1.13g/cm³
• CAS DataBase Reference: Phenol,4-[(1,2,3,4,5,6,7,8-octahydro-1-isoquinolinyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol,4-[(1,2,3,4,5,6,7,8-octahydro-1-isoquinolinyl)methyl]-(74570-02-8)
• EPA Substance Registry System: Phenol,4-[(1,2,3,4,5,6,7,8-octahydro-1-isoquinolinyl)methyl]-(74570-02-8)

Safety Data

• Hazardous Substances Data: 74570-02-8(Hazardous Substances Data)

Upstream product

• 51072-36-7 (+)-1-(p-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline 
• 104-01-8 4-Methoxyphenylacetic acid 
• 3399-73-3 2-(1-cyclohexenyl)ethylamine 
• 51072-34-5 N-(2-cyclohex-1-enylethyl)-2-(4-methoxyphenyl)-acetamide 
• 51072-35-6 1-(4-methoxybenzyl)-3,4,5,6,7,8-hexahydro-isoquinoline 
• 93477-35-1 (+/-)-1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline hydrobromide 
• 102558-14-5 (4-benzyloxy-phenyl)-acetic acid-(2-cyclohex-1-enyl-ethylamide) 
• 30356-07-1 (1S)-1-[(4-methoxyphenyl)methyl]-1,2,3,4,5,6,7,8-octahydroisoquinoline 
• 74570-02-8 (+)-1-(p-hydroxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline 

Downstream Products

• 102558-09-8 4-((R)-2-benzyl-1,2,3,4,5,6,7,8-octahydro-[1]isoquinolylmethyl)-phenol 
• 102666-11-5 4-((R)-2-phenethyl-1,2,3,4,5,6,7,8-octahydro-[1]isoquinolylmethyl)-phenol 
• 67553-46-2 4-((R)-2-methyl-1,2,3,4,5,6,7,8-octahydro-[1]isoquinolylmethyl)-phenol 
• 67553-46-2 4-((S)-2-methyl-1,2,3,4,5,6,7,8-octahydro-[1]isoquinolylmethyl)-phenol 
• 102558-09-8 4-((S)-2-benzyl-1,2,3,4,5,6,7,8-octahydro-[1]isoquinolylmethyl)-phenol 
• 806596-93-0 4-(5,6,7,8-tetrahydro-[1]isoquinolylmethyl)-phenol 
• 74570-02-8 4-((R)-1,2,3,4,5,6,7,8-octahydro-[1]isoquinolylmethyl)-phenol 
• 74570-02-8 4-((S)-1,2,3,4,5,6,7,8-octahydro-[1]isoquinolylmethyl)-phenol 
• 94006-07-2 (+/-)-1-(p-hydroxybenzyl)-2-formyl-1,2,3,4,5,6,7,8-octahydroisoquinoline 
• 94006-07-2 (S)-(+)-N-formyl-1-(p-hydroxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline 
• 71-82-9 levallorphan tartarate 
• 152-02-3 levallorphan 
• 77-07-6 Levorphanol 
• 116597-85-4 ent-17-benzyl-morphinan-3-ol 

Relevant articles and documents

Method for preparing levallorphan tartrate

The invention provides a method for preparing levallorphan tartrate and belongs to the technical field of drug and chemical synthesis. The method takes methoxyphenylacetic acid and 2-(cyclohexenyl)ethylamine as initial raw materials, and comprises nine reaction steps such as acylation condensation, Bischler-Napieralski ring formation reaction, imine reduction, ether bond hydrolysis, resolution, N-alkylation, Grewe cyclization reaction, and salifying. According to the method, the levallorphan tartrate and each intermediate can be obtained at high yield and high purity, and the method can serve as an industrial method for performing large-scale production.

PROCESS FOR MAKING OPTICALLY ACTIVE NAPHTHO[1,2-B][1,4]THIAZEPIN-4(5H)-ONES

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