74586-54-2

Usage

Uses

Used in Pharmaceutical Industry:
3-Iodo-5-methylbenzenamine is used as a chemical intermediate for the synthesis of pharmaceuticals. It serves as a building block in the production of biologically active compounds, contributing to the development of new medications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-iodo-5-methylbenzenamine is utilized as an intermediate in the synthesis of agrochemicals. Its role in creating specific organic materials aids in the production of effective agricultural products.
Used in Organic Material Production:
3-iodo-5-methylbenzenamine is also used as an intermediate in the synthesis of organic materials. Its unique structure allows for the creation of materials with tailored properties for various applications.

Upstream product

• 89-62-3 4-methyl-2-nitroaniline 
• 123158-77-0 2-amino-5-methyl-3-nitrophenyliodide 
• 618-61-1 3-methyl-5-nitro-aniline 
• 618-85-9 3,5-dinitrotoluene 
• 123158-78-1 1-iodo-3-methyl-5-nitrobenzene 

Downstream Products

• 1378998-38-9 4-chloro-N-(3-iodo-5-methylphenyl)pyrimidin-2-amine 
• 1378998-36-7 2-[(3-iodo-5-methylphenyl)amino]pyrimidin-4(3H)-one 

Relevant academic research and scientific papers

Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders

4-Oxo-1,4-dihydroquinoline compounds having a 2-acidic group or a group convertible thereto in vivo, and their pharmaceutically acceptable salts, are potent specific antagonists of N-methyl-D-aspartate (NMDA) receptors and are therefore useful in the treatment of neurodegenerative disorders. 4-Oxo-1,4-dihydroquinoline compounds having a 2-acidic group or a group convertible thereto in vivo, other than carboxy or C 1-6 alkoxycarbonyl, are novel compounds, as also are compounds of formula II STR1 wherein R 2 represents carboxy or a group convertible thereto in vivo, R 6 is hydrogen and R 5 and R 7 represent C 1-6 alkyl or halogen, provided that R 5 and R 7 are not simultaneously chlorine or simultaneously bromine; a process for preparing the novel compounds is described, as also are pharmaceutical compositions containing the novel compounds.

The Kinetics of the Reactions of Picryl Chloride with Some Substituted Anilines. Part 5.

Arrhenius parameters have been measured for the reactions of picryl chloride with the following substituted anilines in acetonitrile: 3-amino- and 3-methyl-aniline, 3-amino-5-nitroaniline, 3-fluoro-5-methylsulphonylaniline, 3-X-5-methylanilines (X=NO2, OMe, CH3, F, Cl, Br, or I) and 3,5-X2-anilines (X = F, Cl, Br, or I).A total of 33 3,5-disubstituted anilines have now been examined for the additivity of substituent effects on the free energy of activation, and it has been shown that with the exception of 3-amino-5-nitroaniline this hypothesis reproduces experimental rate constants within a factor of 2.A rationalization is proposed for the deviations that occur in some cases when more stringent criteria of additivity are used.