7459-29-2Relevant articles and documents
Studies on the synthesis, surface activity and the ability to form pH-regulated wormlike micelles with surfactant containing carboxyl group
Yan, Zhihu,Qian, Feng,Sun, Haonan,Lu, Xia,Li, Yu,Lv, Haibin,Dai, Caili,Jiao, Minglian
, (2020/05/11)
In this article, a series of pH regulated surfactants with different hydrophobic chain length and carboxyl group molecular structure positions were designed and synthesized. The molecular structure of pH regulated surfactants was analyzed by mass spectrometry and 1H NMR spectroscopy. The results of the surface activity test show that the pH regulated surfactants have lower surface tension, which indicates that it is easier to adsorb directionally at the gas-liquid interface and to aggregate in solution. Both inorganic and organic counterions can improve the viscosity of the system to some extent, but the viscosity-increasing ability of organic counterions is much higher than that of inorganic counterions. The results of rheology and dynamic light scattering show the transition from spherical micelles to wormlike micelles was observed when pH increased from 5 to 8 in the Docos-13-enoylamino-acetic acid (Gly-22)/Trimethylstearylammonium chioride (ODAC) system. The results of Cryo-transmission electron microscopy verify this result directly. Also, the experimental results show that the Gly-22/ODAC system has excellent pH cycle regulation performance, which can significantly reduce the application cost of the system.
Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides
Vudhgiri, Srikanth,Koude, Dhevendar,Veeragoni, Dileep Kumar,Misra, Sunil,Prasad,Jala, Ram Chandra Reddy
supporting information, p. 3370 - 3373 (2017/07/07)
In the present study, the synthesis of 1, 3, 4-thiadiazole-based thioglycosides were accomplished in good yields with employing a convergent synthetic route. The starting material 5-amino-1, 3, 4-thiadiazole-2-thiol and followed by a series of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thiols (4a–4j) were synthesized with different fatty acid chlorides. The glycosylation of compounds 4a–4j were achieved with trichloroacetimidate methodology. Antimicrobial and cytotoxicity activities of title compounds were evaluated. Among the entire compounds lauric acid and myristic acid derivatives showed good and moderate antimicrobial activity. In case of cytotoxicity results of compounds 8a–8j and 9a–9j, the acetate protected short chain (C6:0, C8:0, C10:0) compounds and the free hydroxyl long chain saturated (C16:0, C18:0) and unsaturated (C18:1, C22:1) compounds exhibited good activity against different cancer cell lines. Further, the free hydroxyl compounds 9a, 9c–9j did not show any toxicity towards normal CHO-K1 cell line whereas acylated compounds 8a–8j exhibited toxicity.
Screening of a selection of commercially available homogeneous Ru-catalysts in valuable olefin metathesis transformations
Caijo, Frederic,Tripoteau, Fabien,Bellec, Aurelien,Crevisy, Christophe,Basle, Olivier,Mauduit, Marc,Briel, Oliver
, p. 429 - 435 (2013/03/14)
A library of thirteen different commercially available Ru-based catalysts was evaluated in valuable metathesis reactions for the production of fragrance and bioactive molecule precursors. Rigorous library screening clearly illustrated the different catalytic behaviour of the catalyst selection and highlighted its significant advantage to provide efficiency in specific metathesis applications. Interestingly, this strategy offered substantial improvement over the state of the art, with the efficient synthesis of the macrocyclic Exaltolide 2 at low catalyst loading and dilution conditions. The Royal Society of Chemistry 2013.
