74590-73-1

Basic information

• Product Name: 1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene
• Synonyms: 1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene
• CAS NO: 74590-73-1
• Molecular Weight: 260.481
• Mol File: 74590-73-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene(74590-73-1)
• EPA Substance Registry System: 1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene(74590-73-1)

Safety Data

• Hazardous Substances Data: 74590-73-1(Hazardous Substances Data)

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 62269-44-7 methyl 3-trimethylsiloxybut-2-enoate 
• 75-77-4 chloro-trimethyl-silane 
• 26766-99-4 3-(trimethylsilanyloxy)but-2-enoic acid methyl ester 

Downstream Products

• 83467-67-8 C₃₁H₂₈O₁₀ 
• 74590-80-0 methyl (3-hydroxy-2-methoxycarbonyl-5-methylphenyl)acetate 
• 119-36-8 methyl salicylate 
• 124851-57-6 (1S,5R)-1-Methyl-3-oxo-9-oxa-bicyclo[3.3.1]nonane-2-carboxylic acid methyl ester 
• 83578-32-9 methyl 2,6-dihydroxy-4-pentylbenzoate 
• 54620-78-9 6-(1'-benzyloxypentyl)-5,6-dihydro-4-methoxypyran-2-one 
• 54620-78-9 6-(1'-benzyloxypentyl)-5,6-dihydro-4-methoxypyran-2-one 
• 218435-13-3 (5R,6R)-5-Hydroxy-6-(4-methoxy-benzyloxy)-3-oxo-heptanoic acid methyl ester 

Relevant articles and documents

Neighboring group participation in Lewis acid-promoted [3 + 4] and [3 + 5] annulations. The synthesis of oxabicyclo[3.n.1]alkan-3-ones

Lewis acids are employed as catalysts in the annulation of 1,4- and 1,5-dicarbonyl dielectrophiles with bis(trimethylsilyl) end ethers of β-diketones and β-keto esters. A variety of 2-(alkoxycarbonyl)-m-oxabicyclo[3.n.1]alkan-3-ones can be constructed by this process in which two new carbon-carbon bonds are generated. Unusually high regiocontrol is observed, and good to excellent stereochemical control can be achieved at virtually every position on the new carbocycles. Intramolecular neighboring group participation is proposed to explain the unusually high selectivities attained in the annulation reaction.

Hauser-Heck: Efficient Synthesis of γ-Aryl-β-ketoesters en Route to Substituted Naphthalenes

γ-Aryl-β-ketoesters can be prepared in one step from aryl bromides and bis(trimethylsilyl) enol ethers using catalytic amounts of Pd(dba)2/t-Bu3P and stoichiometric amounts of Bu3SnF. The wide range of γ-(hetero)aryl-β-ketoesters that can be obtained illustrate the scope and limitations of this novel Hauser-Heck combination. γ-Aryl-β-ketoesters with a 1,3-dioxane acetal in the ortho position can easily be transformed into the hydroxy naphthoate in very good yield. Aqueous formic acid at 65 °C provides optimal conditions for this deprotective aromatization.

BRIDGE-SUBSTITUTED TROPANES FOR METHODS OF IMAGING AND THERAPY

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