74590-80-0Relevant academic research and scientific papers
Synthesis of homophthalates by [3+3] cyclocondensation reactions of 1,3-bis(silyloxy)-1,3-butadienes with silylated methyl 3,5-dioxohexanoate
Hefner, Jennifer,Villinger, Alexander,Langer, Peter
, p. 831 - 835 (2013)
Homophthalates were prepared by formal [3+3] cyclocondensation of 1,3-bis(silyl enol ethers) with silylated methyl 3,5-dioxohexanoate.
Chemistry of enol silyl ethers. A general synthesis of 3-hydroxyhomophthalates and a biomimetic synthesis of sclerin
Brownbridge, P.,Chan, T. H.,Brook, M. A.,Kang, G. J.
, p. 688 - 693 (2007/10/02)
A general synthesis of 3- hydroxyhomophthalates is developed and applied to the synthesis of sclerin (24), a compound possessing plant-growth activity; the critical step in the synthesis of 24 can be considered as the controlled condensation of a di-β-carbonyl unit with a tri-β-carbonyl unit.
Biomimetic Synthesis of Sclerin
Chan, Tak-Hang,Brownbridge, Peter
, p. 20 - 21 (2007/10/02)
A general synthesis of 3-hydroxy-homophthalates is developed and applied to the synthesis of sclerin (1), a compound possessing plant-growth activity; the critical step in the synthesis of (1) can be considered as the controlled condensation of a dicarbon
A Novel Cycloaromatization Reaction. Regiocontrolled Synthesis of Substituted Methyl Salicylates
Chan, Tak-Hang,Brownbridge, Peter
, p. 3534 - 3538 (2007/10/02)
A new method of constructing six-membered rings, involving the condensation of two three-carbon units, one with two nucleophilic sites and the other containing two electrophilic sites, is reported.The regiochemistry of the reaction is controlled by the differential reactivities of these sites. 1,3-Bis(trimethylsiloxy)-1-methoxybuta-1,3-diene (1) constitutes the three-carbon fragment with two nucleophilic sites.Condensation of 1 with various equivalents of β-dicarbonyl compounds and titanium tetrachloride gave substituted methyl salicylates.The regiochemistry is controlled by the order of reactivity of the electrophilic sites, which is conjugate position of enone > ketone > monothioacetal, acetal.
