74592-59-9Relevant academic research and scientific papers
Synthesis of (dl)-trichodiene using novel ring transformation reaction
Tanaka,Sakai
, p. 5581 - 5584 (2007/10/02)
Synthesis of (dl)-trichodiene has been completed via novel ring transformation reaction using TsOH/ethylene glycol.
66. β-Cleavage of Potassium bicyclooct-5-en-2-olates. Stereoselective Synthesis of (+-)-Trichodiene
Snowden, Roger L.,Brauchli, Robert,Sonnay, Philippe
, p. 570 - 593 (2007/10/02)
The transformation of 12 bicyclooct-5-en-2-ols (V or VI) to 3-(cyclohex-3-enyl)-2-alkanones (III or IV), via β-cleavage of their potassium alkoxides in HMPA, has been investigated (cf. table I).As an illustration of this synthetic methodology, a stereoselective synthesis of (+)-trichodiene ((+)-1) is described wich involves the β-cleavage of the tricyclic potassium alkoxides 46a and 47a to cyclopentanone 4 (cf.Scheme 7).
Stereoselective Total Synthesis of (+/-)-Trichodiene: Biogenetic Precursor of the Trichothecane Sesquiterpenoids
Welch, Steven C.,Rao, A.S.C. Prakasa,Gibbs, Charles G.,Wong, Rayman Y.
, p. 4077 - 4085 (2007/10/02)
Two approaches to the total synthesis of (+/-)-trichodiene (1) are reported from cis-fused lactone 10.Sequential alkylation of lactone 10 was observed to be highly stereoselective as established by the construction of diastereomeric lactone esters 12 and
