746-53-2

Basic information

• Product Name: 2,4,5,7-TETRANITRO-9-FLUORENONE
• Synonyms: 2,4,5,7-TETRANITRO-9-FLUORENONE;2,4,5,7-TETRANITRO-9H-FLUOREN-9-ONE;TNFN;2,4,5,7-tetranitro-9h-fluoren-9-on;2,4,5,7-tetranitro-fluoren-9-on;2,4,5,7-Tetranitrofluoren-9-one;2,4,5,7-Tetranitrofluorenone;9H-Fluoren-9-one, 2,4,5,7-tetranitro-
• CAS NO: 746-53-2
• Molecular Formula: C₁₃H₄N₄O₉
• Molecular Weight: 360.19
• EINECS: 212-018-8
• Mol File: 746-53-2.mol

Chemical Properties

• Melting Point: 252-253 °C
• Boiling Point: 492.26°C (rough estimate)
• Flash Point: 318.4°C
• Appearance: /
• Density: 1.5946 (rough estimate)
• Vapor Pressure: 4.07E-15mmHg at 25°C
• Refractive Index: 1.6120 (estimate)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,4,5,7-TETRANITRO-9-FLUORENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,5,7-TETRANITRO-9-FLUORENONE(746-53-2)
• EPA Substance Registry System: 2,4,5,7-TETRANITRO-9-FLUORENONE(746-53-2)

Safety Data

• RIDADR: 0475
• HazardClass: 1.1D
• Hazardous Substances Data: 746-53-2(Hazardous Substances Data)

Usage

Uses

Used in Explosives and Propellants Industry:
2,4,5,7-Tetranitro-9-fluorenone is used as a high-energy ingredient in the manufacturing of explosives and propellants, leveraging its high energy content for these applications.
Used in Dyes and Pigments Industry:
As a powerful oxidizing agent, 2,4,5,7-Tetranitro-9-fluorenone is utilized in the production of dyes and pigments, contributing to the development of vibrant and stable colorants.
Used in Photodynamic Therapy Research:
2,4,5,7-Tetranitro-9-fluorenone has been studied for its potential use as a sensitizing agent in photodynamic therapy for the treatment of cancer, exploring its ability to enhance the therapeutic effects of light-based cancer treatments.

InChI:InChI=1/C13H4N4O9/c18-13-7-1-5(14(19)20)3-9(16(23)24)11(7)12-8(13)2-6(15(21)22)4-10(12)17(25)26/h1-4H

Upstream product

• 486-25-9 9-fluorenone 
• 29210-71-7 2,4,5,7-tetranitro-9H-fluorene 
• 947-84-2 2-Biphenylcarboxylic acid 

Downstream Products

• 50996-73-1 (S)-<<(tetranitrofluorenylidene)amino>oxy>propionic acid 
• 66069-40-7 R(+/-)2-(2,4,5,7-tetranitro-9-fluorenyloximino)propanoic acid 
• 15517-55-2 2,4,5,7-tetranitro-9-dicyanomethylenefluorene 
• 1426674-62-5 2-phenoxy-4,5,7-trinitro-9H-fluoren-9-one 
• 1426674-77-2 2-phenylsulfanyl-4,5,7-trinitro-9H-fluoren-9-one 
• 5001-45-6 (+)-2-(2,4,5,7-Tetranitro-9-fluorenylidenamino-oxy)-propionsaeure 
• 279216-45-4 2-butylsulfinyl-4,5,7-trinitrofluoren-9-one 
• 78369-54-7 2,4,5,7-Tetranitro-fluoren-9-one; compound with 4-amino-benzoic acid 2-diethylamino-ethyl ester 

Relevant articles and documents

Nitroaromatics as n-type organic semiconductors for field effect transistors

The nitro group (NO2) is one of the most common electron-withdrawing groups but it has rarely been used in the design of organic semiconductors (OSCs). Herein, we report the n-type semiconducting behavior of simple fluorenone derivatives functionalized with NO2and CN groups. While the electron mobilities measured in the thin film field-effect transistors are modest (10?6-10?4cm2V?1s?1), the nitrofluorenone OSCs offer excellent air-stability and remarkable tunability of energy levelsviafacile modification of the substitution pattern. We study the effect of substituents on the electrochemical properties, molecular and crystal structure, and the charge transport properties of nitrofluorenones to revitalize the underestimated potential of NO2functionalization in organic electronics.

Camptothecin derivatives as chemoradiosensitizing agents

Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.

SYNTHESIS OF POLYNITRO-SUBSTITUTED 2-CARBOXYBIPHENYLS

Methods were developed for the synthesis of polynitro-substituted 2-carboxybiphenyls.During the nitration of 2-carboxybiphenyl under rigorous conditions or during the heating of nitro-substituted 2-carboxybiphenyls in concentrated sulfuric acid or high-strength oleum decarboxylation and cyclization occur with the formation of nitro-substituted biphenyls and fluorenone.