7461-66-7Relevant academic research and scientific papers
MODEL STUDIES FOR INSECT PROTEIN SCLEROTIZATION: OXIDATIVE LOSS OF THE SIDE CHAIN FROM 4-SUBSTITUTED CATECHOLS
Pyne, Stephen G.,Truscott, Roger J. W.,Maxwell, Karin,Morales, M. Carmen,Walsh, Bernadette C.,Wynn, Barbra L.
, p. 661 - 670 (2007/10/02)
The oxidation of several 4-substituted catechols in aqueous solution, pH7 in the presence of aniline results in the formation of 4,5-dianilino-1,2-benzoquinone 2 and the anil of 2 (3).The C-4 substituent is efficiently cleaved and mechanisms are proposed to account for this phenomenon based on HPLC and GC studies and the formation of N-methylaniline when these reactions were performed in the presence of sodium cyanoborohydride.The evidence suggests that the initial step involves the addition of aniline to the catechol C-4 side chain.
