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3-(dimethylamino)-1,1,2-triphenylpropan-1-ol, also known as propranolol, is a beta-adrenergic blocking agent belonging to the class of beta-blockers. It is a racemic mixture of two enantiomers, S(-)-propranolol and R(+)-propranolol, with the S(-) enantiomer being the more active form. Propranolol is primarily used in the treatment of various cardiovascular conditions, such as hypertension, angina, arrhythmias, and myocardial infarction. It works by competitively inhibiting the action of catecholamines on beta-adrenergic receptors, thereby reducing heart rate, blood pressure, and cardiac output. Additionally, propranolol has applications in the management of anxiety, migraines, and certain tremors. The chemical structure consists of a dimethylamino group attached to a triphenylpropanol backbone, which contributes to its pharmacological properties.

7464-67-7

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7464-67-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7464-67-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,6 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7464-67:
(6*7)+(5*4)+(4*6)+(3*4)+(2*6)+(1*7)=117
117 % 10 = 7
So 7464-67-7 is a valid CAS Registry Number.

7464-67-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(dimethylamino)-1,1,2-triphenylpropan-1-ol

1.2 Other means of identification

Product number -
Other names 3-N,N-Dimethylamino-1,1,2-triphenyl-propan-1-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7464-67-7 SDS

7464-67-7Relevant academic research and scientific papers

Direct benzylic metalation of a phenethylamine derivative: Potassium as the key to both generation and stabilization of a labile anion

Unkelbach, Christian,Rosenbaum, Hannah S.,Strohmann, Carsten

supporting information, p. 10612 - 10614,3 (2020/09/02)

t-BuLi-t-BuOK selectively metalates the benzylic position of 2-phenylethyldimethylamine under mild conditions without occurrence of β-elimination in the resulting metalated species. Theoretical and structural studies indicate that potassium is crucial for both the lowering of the barrier of the initial deprotonation step and the stabilization of the labile anion.

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