7465-44-3

Upstream product

• 7404-32-2 methyl 2,3,4-tri-O-acetyl-6-bromo-6-deoxy-α-D-glucopyranoside 
• 10368-81-7 methyl 4-O-benzoyl-6-bromo-6-deoxy-α-D-glucopyranoside 
• 97-30-3 methyl-alpha-D-glucopyranoside 

Downstream Products

• 23701-87-3 methyl 6-azido-6-deoxy-α-D-glucopyranoside 
• 5155-47-5 methyl 6-amino-6-deoxy-α-D-glucopyranoside 
• 6893-93-2 methyl 2,3-di-O-benzoyl-6-deoxy-4-O-(p-tolylsulfonyl)-α-D-glucopyranoside 
• 51236-51-2 methyl 2,4-di-O-benzoyl-6-deoxy-α-D-glucopyranoside 
• 51236-52-3 methyl 2,3-di-O-benzoyl-6-deoxy-α-D-glucopyranoside 
• 51236-53-4 methyl 2,3,4-tri-O-benzoyl-6-deoxy-α-D-glucopyranoside 
• 1373434-24-2 benzyl (2-methyl-4-((((2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)methyl)sulfonyl)butan-2-yl)carbamate 
• 5155-43-1 methyl 6-deoxy-α-D-glucopyranoside 
• 130471-81-7 (2S,3S,4R)-1-Benzylamino-hex-5-ene-2,3,4-triol 
• 73111-14-5 3,4,5-tris(benzyloxy)-2-(bromomethyl)-6-methoxytetrahydro-2H-pyran 
• 7404-32-2 methyl 2,3,4-tri-O-acetyl-6-bromo-6-deoxy-α-D-glucopyranoside 
• 14169-22-3 methyl 2,3,4-tri-O-benzoyl-6-bromo-6-deoxy-α-D-glucopyranoside 
• 135216-49-8 methyl 2,3-di-O-benzoyl-6-bromo-6-deoxy-α-D-glucopyranoside 

Relevant academic research and scientific papers

ANTIMICROBIAL POLYETHER AND POLYOL COMPOUNDS

The present application describes compounds of Formula I and Formula IA and as disclosed herein, that are useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.

A novel protocol for the regioselective bromination of primary alcohols in unprotected carbohydrates or glycosides

The regioselective and efficient bromination of primary hydroxyl groups in unprotected carbohydrates or glycosides is successfully achieved by using (chloro-phenylthio-methylene)dimethylammoniumchloride (CPMA) in the presence of tetrabutylammonium bromide

METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID

The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to, the prevention and treatment of Alzheimer's disease.

Novel drug delivery compositions

The present invention provides for a novel molecules useful for delivery of compounds to a mammal, more particularly for the intracellular delivery of nucleotides, nucleotide analogues or compounds with a heterocyclic base. Also provided for are novel therapeutic complexes comprising novel molecules complexed with nucleotide analogues or heterogeneous or homogenous oligomers comprised of nucleotide analogues.

Synthesis of thioglycosides by tetrathiomolybdate-mediated michael additions of masked thiolates

An efficient one-pot methodology for the synthesis of thioglycosides in excellent yields under neutral conditions through the use of benzyltriethylammonium tetrathiomolybdate [(BnNEt3) 2MoS4; 1] as a sulfur-transfer reagent has been developed. The reagent 1 reacts with sugar halides to give sugar disulfides, which then undergo reductive cleavage in situ to provide the corresponding thiolates, followed by Michael addition to give the corresponding thioglycosides. Further, the utility of this one-pot reaction in aqueous medium has been exemplified through the use of ammonium tetrathiomolybdate [(NH4)2 MoS4; 2]. The application of this methodology has been extended to the synthesis of a variety of thiosugar analogues with excellent diastereoselectivity through inter- and intramolecular reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Halogenation of carbohydrates by triphenylphosphine complex reagents in highly concentrated solution under microwave activation or conventional heating

Halogenation of carbohydrates with triphenylphosphine and carbon tetrachloride, hexachloroethane or 1,2-dibromotetrachloroethane was shown to be very efficient in highly concentrated solutions of nonpolar solvents such as toluene or 1,2-dichloroethane, wi

New glycoconjugated cyanine dyes as fluorescent labeling reagents

New highly water soluble cyanine dyes incorporating methyl glucopyranoside residues and reactive functionality are synthesised. The new dyes are conjugated to aminodextrans and to antibodies. The absorption and fluorescence properties of the new dyes and of the labeled substrates are discussed.

Multichromophoric Cyclodextrins. 1. Synthesis of O-Naphthoyl-β-cyclodextrins and Investigation of Excimer Formation and Energy Hopping

The synthesis and photophysical properties of β-cyclodextrins bearing seven 2-naphthoyloxy chromophores in specific positions, either on the primary face or the secondary face, or 14 2-naphthoyloxy chromophores, seven on each face, are reported. These multichromophoric cyclodextrins are good models for the study of excitation energy migration among chromophores in well-defined positions. The investigation was performed in dichloromethane and in a mixture of ethanol and methanol that can form a glass at low temperature. The absorption spectra show that the interactions between chromophores in the ground state are weak, whereas the fluorescence spectra reveal the existence of excimers at room temperature but not at low temperature in a rigid glass. Further evidence of excimer formation is provided by the fluorescence decays. Since excimers act as energy traps, the energy hopping process was studied in a rigid glass at low temperature by steady-state and time-resolved fluorescence depolarization techniques. The steady-state anisotropy is found to be one seventh of the theoretical limiting anisotropy 0.4, which means that excitation energy hops between chromophores with essentially randomly oriented transition moments at a rate much higher than the chromophore intrinsic decay rate. Energy hopping is indeed very fast as shown by the fluorescence anisotropy decay which is at least as fast as the apparatus time resolution (a few tens of picoseconds).

The synthesis of new glycoside surfactants by means of halogenated sugars. Thioethers and methyl sulfone derivatives of α-D-glucoside and α-D-mannoside

We describe an efficient synthesis of methyl 6-halogeno-6-deoxyglycosides which was performed using Ph3P-X2 in DMF solution. Carbohydrate halides could thus be isolated in high yields without preliminary protection of the secondary hydroxyl groups, and were used as intermediates for the preparation of 6-alkylthio- and 6-alkylsulfonyl-6-deoxy glycosides. These derivatives are new non-ionic chiral surfactants.