74686-89-8Relevant academic research and scientific papers
Synthesis of substituted β-lactones by a Reformatsky reaction of carbonyl compounds, phenyl α-bromoalkanoates, and indium
Schick, Hans,Ludwig, Ralf,Kleiner, Katharina,Kunath, Annamarie
, p. 2939 - 2946 (2007/10/02)
Di-, tri-, and tetrasubstituted β-lactones are accessible in a one-step procedure by a Reformatsky reaction of phenyl α-bromoalkanoates with ketones or aldehydes at a sacrificial indium anode. With indium powder comparable results are obtained. The yield of β-lactones is significantly lower, if zinc is used instead of indium.
