74738-03-7

Upstream product

• 21272-85-5 phenylsulfonylnitromethane 
• 873-55-2 sodium benzenesulfonate 
• 74737-89-6 phenylsulfonylnitromethane sodium salt 
• 100-39-0 benzyl bromide 

Downstream Products

• 74737-91-0 1-nitro-1-(phenylsulfonyl)pentane 
• 74737-98-7 1-nitro-1-(phenylsulfonyl)-2-undecene 
• 143346-12-7 (3aS,6aR)-3-Benzenesulfonyl-4,6a-dihydro-3aH-cyclopenta[d]isoxazole 2-oxide 
• 143346-19-4 (3aS,7aR)-3-Benzenesulfonyl-3a,4,5,7a-tetrahydro-benzo[d]isoxazole 2-oxide 
• 76024-93-6 α-(phenylsulfonyl)benzaldoxime 
• 74737-93-2 4-chloro-1-nitro-1-(phenylsulfonyl)butane 
• 74737-92-1 1-nitro-1-(phenylsulfonyl)octane 
• 74737-96-5 1-methyl-2-<2-nitro-2-(phenylsulfonyl)-ethyl>benzene 
• 74737-95-4 4-nitro-1-<2-nitro-2-(phenylsulfonyl)-ethyl>benzene 
• 74737-89-6 phenylsulfonylnitromethane sodium salt 
• 74737-90-9 1-nitro-1-(phenylsulfonyl)ethane 
• 74737-94-3 <2-nitro-2-(phenylsulfonyl)ethyl>-benzene 
• 111189-94-7 {9-[(3aR,4R,6S,6aS)-6-(Benzenesulfonyl-nitro-methyl)-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl]-9H-purin-6-yl}-carbamic acid methyl ester 
• 111189-94-7 {9-[(3aR,4S,6R,6aS)-6-(Benzenesulfonyl-nitro-methyl)-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl]-9H-purin-6-yl}-carbamic acid methyl ester 

Relevant academic research and scientific papers

α-NITRO SULFONES. 2. CONVENIENT NEW SYNTHESIS AND SELECTED FUNCTIONAL GROUP TRANSFORMATIONS

(Phenylsulfonyl)nitromethane (1) is preferentially C-alkylated by benzylic halides and primary alkyl iodides, affording secondary α-nitro sulfone products. α-Nitro sulfones are also obtained from the corresponding C-alkylation of allylic acetates in the presence of catalytic tetrakis(triphenylphosphine)palladium.The palladium(0)-catalyzed reaction is stereospecific for geranyl and neryl acetates and is also regioselective.Desulfonation of α-nitro sulfones is readily accomplished by light-induced reduction with 1-benzyl-1,4-dihydronicotinamide (BNAH).Reduction of secondary α-nitro sulfones with 20percent aqueous titanium(III) chloride affords nitriles.Oxidation with alkaline permanganate affords carboxylic acids.