7474-15-9

Usage

Uses

Used in Organic Synthesis:
(2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol is utilized as a key intermediate in organic synthesis for the creation of various complex organic molecules. Its unique structure and reactivity make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, (2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol serves as a building block for the development of new drugs. Its hydroxyimino functional group can be exploited to form novel drug candidates with potential therapeutic applications.
Used in Industrial Applications:
(2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol may also find use in various industrial applications, such as in the production of specialty materials, coatings, or as a component in the formulation of various chemical products. Its versatility and reactivity contribute to its potential utility across different industries.

Upstream product

• 119-51-7 1-phenyl-1,2-propanedione 2-oxime 
• 781-35-1 1,1-diphenylacetone 
• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 
• 33718-91-1 1,1-diphenyl-1-bromo-2-propanone 
• 4571-02-2 1-hydroxy-1,1-diphenyl-2-propanone 

Downstream Products

• 25683-83-4 2,3,3-triphenylacrylaldehyde 
• 89030-17-1 3-Ethyl-2,2-diphenyl-1-aza-bicyclo[1.1.0]butane 
• 89030-16-0 2,2,3-triphenyl-1-azabicyclo<1.1.0>butane 
• 64890-05-7 5-Ethyl-4,4-diphenyl-3-oxa-1-aza-bicyclo[3.1.0]hexan-2-one 
• 64890-04-6 4,4,5-Triphenyl-3-oxa-1-aza-bicyclo[3.1.0]hexan-2-one 
• 102839-81-6 Carbonic acid diphenyl-(2-phenyl-aziridin-2-yl)-methyl ester ethyl ester 
• 102839-82-7 5-Isopropyl-4,4-diphenyl-3-oxa-1-aza-bicyclo[3.1.0]hexan-2-one 
• 64889-89-0 diphenyl(2-phenyl-aziridin-2-yl)methanol 
• 64889-90-3 (2-ethyl-aziridin-2-yl)diphenylmethanol 
• 102839-77-0 (2-Isopropyl-aziridin-2-yl)-diphenyl-methanol 

Relevant academic research and scientific papers

A rare ligand bridged ferromagnetically coupled MnIV3 complex with a ground spin state of S = 9/2

An exclusively chelating ligand bridged high-valent [MnIV 3] complex has been synthesized, in which all MnIV ions are ferromagnetically-coupled to exhibit an ST = 9/2 spin ground state. The Royal Society of Chem

Intermolecular Cope-type hydroamination of alkenes and alkynes using hydroxylamines

The development of the Cope-type hydroamination as a method for the metal- and acid-free intermolecular hydroamination of hydroxylamines with alkenes and alkynes is described. Aqueous hydroxylamine reacts efficiently with alkynes in a Markovnikov fashion to give oximes and with strained alkenes to give N-alkylhydroxylamines, while unstrained alkenes are more challenging. N-Alkylhydroxy-lamines also display similar reactivity with strained alkenes and give modest to good yields with vinylarenes. Electron-rich vinylarenes lead to branched products while electron-deficient vinylarenes give linear products. A beneficial additive effect is observed with sodium cyanoborohydride, the extent of which is dependent on the structure of the hydroxylamine. The reaction conditions are found to be compatible with common protecting groups, free OH and NH bonds, as well as bromoarenes. Both experimental and theoretical results suggest the proton transfer step of the N-oxide intermediate is of vital importance in the intermolecular reactions of alkenes. Details are disclosed concerning optimization, reaction scope, limitations, and theoretical analysis by DFT, which includes a detailed molecular orbital description for the concerted hydroamination process and an exhaustive set of calculated potential energy surfaces for the reactions of various alkenes, alkynes, and hydroxylamines.

SYNTHESE PHOTOCHIMIQUE D'AZA-1 BICYCLOBUTANES

Aza-1 bicyclobutanes 2 are readily obtained by photolysis of carbamates 1. 1 are easily synthetised from 3.