7474-93-3

Usage

Uses

Used in Pharmaceutical Industry:
4-(acetylamino)-3-aminophenyl acetate is used as a pain reliever and fever reducer for treating a variety of conditions such as headaches, muscle aches, arthritis, and fevers. It is considered safe when taken in recommended doses, but can cause liver damage if taken in excess.

Upstream product

• 64-17-5 ethanol 
• 2243-69-8 4-acetamido-3-nitrophenyl acetate 
• 103-84-4 Acetanilid 
• 2623-33-8 4-acetoxyacetanilide 

Downstream Products

• 808742-91-8 4-(acetylamino)-3-{[2-chloro-4-(pentyloxy)benzyl]amino}phenyl 
• 808744-70-9 4-(acetylamino)-3-{[(3-chloro-1,1'-biphenyl-4-yl)methyl]amino}phenyl acetate 
• 75258-07-0 1,2-diacetamido-4-acetoxybenzene 

Relevant academic research and scientific papers

Acylamino-Directed Specific Sequential Difunctionalizations of Anilides via Metal-Free Relay Reactions for p-Oxygen and o-Nitrogen Incorporation

Novel acylamino-directed relay disubstitutions realize the sequential difunctionalizations of anilides (1) under mild and metal-free conditions for the first time. This [bis(trifluoroacetoxy)iodo]benzene (PIFA) and BF3·Et2O promoted straightforward reaction produces a series of p-acetoxyl- or p-alkoxyl-o-nitro-N-arylamides (2), which are key scaffolds of various drugs, functional materials, and bioactive molecules. The flexibility with respect to the functional groups in these products affords this novel protocol excellent versatility for synthetic applications.